3.2 SSRIs Flashcards
1
Q
Why is it recommended as 1st line treatment for depression?
A
Effective and has less side effects than other antidepressants
2
Q
Side effects?
A
GI symptoms
Anxiety
Insomnia
Sexual side effects
Increased risk of GI bleeding
Hyponatraemia
3
Q
Citalopram specific points?
A
Risk of QT prolongation
Relatively lower drug interactions
4
Q
Escitalopram specific points?
A
S enantiomer of citalopram, therefore very similar
5
Q
Fluoxetine specific points?
A
More interactions, long half-life and is licensed for children
6
Q
Paroxetine specific points?
A
More interactions, short half-life (withdrawal symptoms)
7
Q
Sertraline specific points?
A
Fewer interactions, safest in history of MI/ unstable angina
