3.15.23_Rafael JOP and JCP Flashcards
What study exxamined the effect of particle size on histology and clinical outcomes?
Basma JOP
RCT
Aim: To compare (clinically and histologically) the quantity and quality of bone gained following LRA (lateral ridge aug) procedures using small-particle (SP)-sized (0.25–1.0 mm) versus (LP)-sized (1.0–2.0 mm) mineralized corticocancellous bone allografts.
The membrane was fixated.
Histology focused on 3 analysis zones:
* Zone 1: coronal third
* Zone 2: middle third
* Zone 3: apical third
NSSD among large vs. small particle sizes **except for soft tissue area **
What are the patient-reported outcomes of palatal donor site healing using four wound dressing modalities after harvesting FGG?
Basma JOP
Aim: To compare 4 common wound management approaches to alleviate patient discomfort a swell as to achieve the best clinical outcomes:
* Control group: Collagen plugs with sutures [CPS]
* Collagen plugs with cyanoacrylate [CPC]
* Platelet-rich fibrin with sutures [PRF],
* Palatal stents [PS])
Pain level evaluation:
* visual analog scale
* number of analgesics consumed
* need for additional analgesics
* amount of swelling
* amount of bleeding
* activity tolerance
* willingness for retreatment
Findings: NSSD among test groups, but SSD between the control and test groups for pain scores in the first 10 days.
What study compared flap versus flapless alveolar ridge preservation?
Siu JOP
RCT.
Control Group: 12 patients , Full-thickness flap
Test Group: 12 patients, Flapless
Aims:
* Primary: to compare a flapless technique of ARP versus a conventional flap technique.
* Secondary: to evaluate the histological composition in order to determine vital bone percentage.
Materials used:
Demineralized bone matrix allograft
Corticocancellous mineralized particulate allograft
Calcium sulfate barrier
Compared horizontal ridge width at crest and 5mm apical to the crest.
Results: NSSD in all measurements except for soft tissue thickness at the occlusal at 4 months - greater height in flapless group (2.3 mm vs. 1.7mm flap group).
What study compared 5 year results of soft tissue augmentation with volume-stable collagen matrix or CTG at implants?
Thoma JOP
Aim: To assess the mucosal thickness, esthetics, peri-implant health, ridge contour changes and patient evaluations of implant sites previously subjected to soft tissue augmentation with either a tissue substitute (VCMX = Fibrogide) or an SCTG 5 years after insertion of final restorations.
Examined:
* Marginal bone levels: radiographs at different time points (distance between the implant shoulder and the first bone-to-implant contact).
* Mucosal thickness: endodontic file 1 mm apical of the mucosal margin on the buccal side
* Ridge contour changes: silicone impression 🡪 casts poured and scanned
* Esthetics: measuring the papilla fill (papilla index), the crown height and the Pink Esthetic Score (PES).
* Patient-reported outcome measures (PROMs): standardized questionnaire (oral health impact profile-G14; OHIP-G14)
Results: NSSD among groups = however, there was huge dropout so technically, conclusions cannot be made
What study looked at the outcomes of alveolar ridge preservation using DBBM-C?
Couso-Queiruga JCP
DBBM-C: collagenated bovine bone xenograft.
Aim: To evaluate the healing outcomes (histology and clinical) in non-molar post-extraction sockets filled with deproteinized bovine bone mineral with collagen (DBBM-C) as a function of time.
3 groups:
* Group A: ARP followed by bone core biopsy/implant placement at 3 months.
* Group B: ARP followed by bone core biopsy/implant placement at 6 months.
* Group C: ARP followed by bone core biopsy/implant placement at 9 months.
Findings: NSSD among groups. Also, the thicker the facial bone thickness upon extraction, the less horizontal alveolar bone resorption over time.
What study compared loading and grafting on hard- and soft-tissue healing at immediate implants in minipigs?
Parvini JCP
14 mini pigs
Aim: To histologically evaluate the influence of:
(1) loading and
(2) grafting
on osseointegration and peri-implant soft-tissue healing at immediately placed, self-cutting progressive tissue-level implants (TLX) in a minipig model.
4 groups:
(1) unloaded (closure cap) with simultaneous grafting using a bovine bone mineral;
(2) unloaded without grafting;
(3) loaded (4.5mm healing abutment) with simultaneous grafting;
(4) loaded without grafting.
Findings: NSSD among bone-implant contact, JE, CTC, bone width. Concluded that implant loading and grafting have no major effects on osseointegration and peri-implant soft tissue healing at TLX implants.
Note: The “loaded” group used a healing abutment only - it wasn’t actual loading
What study examined the effect of periodontal treatment on hBA1C and blood values on Metabolic Syndrome patients?
Milanesi JCP
Aim: To assess the effect of periodontal treatment on HBA1 and diagnostic parameters of patients with metabolic syndrome.
Metabolic syndrome: abnormalities in Triglycerides, HDL-C, fasting blood glucose, SBD, DBD, and waist circumference.
Material & Methods:
157 patients with metabolic syndrome and moderate to severe periodontitis, receiving non-surgical periodontal therapy (n= 79) vs no therapy (n=79)
Non-surgical periodontal therapy (scaling and root planning by manual and ultrasonic instruments, and OH instructions every 4 weeks)
Medical treatment was delivered in both groups as recommended
Measured at 3 and 6 months: HbA1c and MetS parameters (Triglyicerides, HDL-C, fasting blood glucose, SBD, DBD, and waist circumference), CRP and HOMA indexes were assessed at baseline
Findings: Periodontal treatment led to reduction in periodontal clinical parameters, but did not have effect on HBA1c levels, the MetS parameters.
What study examined periodontitis and mortality in a longitudinal cohort study over 50 years?
Bond JCP
Longitudinal cohort study
Aims: Evaluate the association between periodontal health status and all cause mortality.
The hypothesis: increased alveolar bone loss (ABL) would be associated with an increased risk of death
Measurements of bone loss used the Schei ruler, which is a scale from 0 to 5. The 0 is 0% bone loss, 5 is ≥ 80% bone loss.
Mortality: death by any cause was assessed via notification from next of kin or postal authorities in the case of returned mail, and routine checks for death records
Covariates: age, hypertension, BMI. Type2 DM, education, income, cigarette smoking
Results: Each 1-unit increase in the Schei ruler leads to a 14% increase in mortality
