3.1-3.2

Question 1

unique feature of each amino acid

Answer 1

R group

side chain

Question 2

two common types of covalent bonds in proteins

Answer 2

peptide bonds

disulphide bonds b/w Cys

Question 3

convention of writing proteins

Answer 3

amino terminal always written first

Question 4

residue

Answer 4

individual aa when it is in a peptide

Question 5

proteolysis

Answer 5

aka proteolytic cleavage
hydrolysis of a protein by another protein
specific means of cleaving peptide bonds

Question 6

proteolytic enzyme

Answer 6

protease
protein that does the cutting
enzyme which cuts a protein

Question 7

proteolytic cleavage

Answer 7

specific means of cleving peptide bonds

many enzymes cleave peptide bond adjacent to a specific aa

Question 8

formation of peptide bond

Answer 8

lone pair on the amino group of 1 aa attacks the carboxyl group of the other aa
forming a N C C N C C pattern

Question 9

trypsin cleavage

Answer 9

carboxyl side of Arg and Lys

Question 10

chymotrypsin

Answer 10

cleaves adjacent to hydrophobic residues such as Phe

Question 11

Cys special characteristics

Answer 11

has a reactive thiol ( SH) in its side chain
thiol aka sulfhydryl
reacts with thiol of another Cys to produce covalent S-S bond knwn as a disulphide bond

Question 12

role of diS bond

Answer 12

important role in stabilizing tertiary protein structure

Question 13

Cystine vs Cysteine

Answer 13

Cystine
refers to the molecule which is formed once the Cys residues are diS bonded to each other
Cysteine
refers to the individual aa

Question 14

protein structure and function

Answer 14

each protein folds into a unique 3D structure that is required for protein to be functional

Question 15

denatured

Answer 15

improperly folded proteins

are non functional

Question 16

4 levels of protein folding

Answer 16

primary
secondary
tertiary
quaternary
all contributed to final 3D structure
each level depends on a certain type of bond

Question 17

primary sequence

Answer 17

simplest level of protein structure

order aa are bonded to each other in the polypep