3.08.22 John Mazz_Common lab tests

Question 1

What % of common autoimmune diseases are diagnosed via IIF for anti-nuclear antibodies?

Answer 1

Systemic lupus erythematosus: antinuclear antibodies (ANA’s) in 95% of patients
Sjogren’s ANA’s in 75% of patients
Rheumatoid arthritis ANA’s in 30% of pts

Question 2

When are blood tests indicated for patients?

Answer 2

Patients on blood thinners should have INR test
prior to surgery to avoid excessive bleeding.
Acceptable INR < 3

• White blood cell count – for patients with
  HIV, it is important to know the WBC count prior
  to surgery. CD4+ cells should be >500 cells/mm3.
  Normal value for HIV patient is 500-1500
  cells/mm3. If CD4+ < 1500, avoid surgery.
  If CD4+ is < 200, it is AIDS
• Alkaline Phosphatase (ALP) and Total Bilirubin
  tests indicate liver function which may indicate
  increased bleeding risk or contraindication of
  certain drugs (e.g. acetaminophen)

Question 3

What are the normal salivary flow rate?

Answer 3

Normal Salivary Flow:
Stimulated = 1.5-2.0 mL/min
Unstimulated = 0.3-0.4 mL/min
Hyposalivation:
Stimulated ≤ 0.5–0.7 mL/min
Unstimulated ≤0.1 mL/min