305 Flashcards
What does the Artificial Neural Networks constitute
A part of computer science based on neuroscience ideas
What is biological excitation
Internal mechanism
What are the external neurons that enable the propagation
External mechanism
What are propagated by a neuron
Spikes
Describe a neuron
Able to propagate signals over large distances
Propagate information by generating electrical pulses (action potentials or spikes) that can travel down nerve fibres.
Specialised for generating electrical signals in response to chemical/other inputs and transmitting them to other cells
Represent and transmit information by firing a sequence of spikes in various temporal patterns
What is the electrical potential between in most living cells
Interiors and (exterior) environment
What is one of the factors determining the energy barriers encountered by charged substances (ions) entering/leaving the cell
The membrane potential
What are ion channels
Proteins within the cell membrane with the central pore through which ions can cross the membrane
What is the function of the cell membrane
It acts as a barrier for ions
What elements are ions predominantly made of
Sodium
Potassium
Calcium
Chloride
How do Ion channels control the flow of ions
By opening and closing in response to voltage changes and both internal/external signals
What causes the response of a large amplitude electrical wave
A significantly large perturbation, above a threshold in intensity and duration
Describe wave propagation in biological excitation
Travels with uniform velocity
Excitation/transmission is all or none- strength does not vary
Excitation is followed by the absolute refractory period, an unexcitable period of definite duration
What is the function of dendrites
Receive inputs from many other neurons through synaptic connections
What is the soma
The cell body
What is the function of the axon
Carries signals from the neuron to other neurons/effectors
What is the name for the tips of axon branches
Boutons/nerve terminals
What is a synapse
The location of interaction between a terminal and the cell
When is a neurotransmitter released
When a spike arrives from the presynaptic neuron
Describe trans-synaptic stimulation
Neurotransmitters cross the synaptic cleft and bind to receptors on the dendrite spine
Excitatory synapses on the cortical pyramid form on dendrite spines or axon
Describe no physiological continuity from neuron to neuron
When an impulse (perturbation) reaches a
synapse, it does not necessarily stimulate the
following neuron
What does trans-synaptic stimulation of a neuron require
Either:
Temporal summation- a repetition of impulses in time at the same synapse
or
Spatial summation- the simultaneous arrival of impulses at a sufficient number of adjacent synapses to make the density of excitation high enough
What is inhibition
The opposite effect of excitation, renders the element less excitable to other stimuli. Can occur due to the arrival of an impulse at synapses
What is the top trace
A recording from an intercellular electrode connected to the soma of the neurone.