3. Wound Healing Flashcards
What do perio therapy and perio disease have in common
they both damage the periodontal tissues
(Regeneration/repair) is the goal of perio therapy
regeneration
Which is more likely to occur after perio therapy (regeneration/repair)
repair
What is regneration
- Lost tissues are completely restored
- New cementum with inserting collagen fibers from PDL cells on a previously peridontally involved root surface with a regrowth of new alveolar bone
(T/F) Complete regeneration is uncommon
T
Define repair
- Replacement of tissues do no replicate the tissues that were lost
- May have an attachment with a long JE
- No formation of new cementum, PDL and alveolar bone
What are the two types a ways wounds heal
primary and secondary intention
Describe primary intention
- Clean incision
- Edges are approximated with sutures, glue, etc.
- Narrow incisional space filled with clotted blood
- Minimal scaring
Describe day 1 of healing with primary intention
- Neutrophils are the first cells to respond
- PMNs migrate to the wound edge into a clot
- Epitheloal cells begin to migrate beneath the surface scab to join at the midline
- Angiogenesis begins with BM and extracellular matrix degradation with capillary sprout formation
Describe day 3 of healing with primary intention
- Macrophages predominate over PMNs
- Endothelial cell migration, proliferation and early organization and maturation
- Granulation tissues starts to fill the incisional space
- Collagen fibers are present but do not connect the incision
Describe day 5 of healing by primary intention
- Granulation tissue fills the incisional space
- Angiogenesis peaks with more organization and maturation
- Collagen fibrils bridge the incision
- Normal epithelium thickens
Describe week 2 of healing by primary intention
-Increased fibroblasts and collagen accumulation
Describe healing be primary intention after 1 month
- Intact epithelium
- Absence of inflammation
- Tissue is still remodeling
Describe secondary intention healing
- Wound edges are not approximated resulting in large tissue defect
- Greater inflammation
- More granulation tissue
- More fibrin and necrotic debris must be removed
- Scar formation with contraction
Scar formation with contraction (does/doesn’t) occur with the attached gingiva for what reason
Doesn’t because of its close approximation with the bone