3) Upper GI Bleeds Flashcards

1
Q

Common causes of GI Bleeds?

A
  • Peptic Ulcer (duodenal>gastric)
  • Gastric Erosions/Gastritis
  • Mallory-Weiss Tear
  • Oesophageal Varices (5% bleeds, 80% mortality)
  • Duodenitis
  • Oesophagits
  • Tumours
  • Dieulafoy Lesions
  • HHT
  • Aortoenteric fistula
  • Clotting Defects
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2
Q

How should patients with GI Bleed be risk assessed?

A

-Blatchford score at first assessment
-Full Rockall Score after endoscopy
Consider early discharge for pts with pre-endoscopy Blatchford score of 0

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3
Q

S+S of GI Bleed?

A
  • Haemtemesis or Melaena
  • Dizziness
  • Abdo Pain
  • Hypotension
  • Postural Hypotension
  • Tachycardia
  • Dec. JVP
  • Dec. Urine Output
  • Signs of chronic liver disease
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4
Q

Initial Management of GI Bleed?

A
Is the Patient Shocked? 
Yes: See separate Card
No: 2 Wide bore cannulae, start saline and monitor vital signs
-Aim to keep Hb >8
-Check Bloods
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5
Q

How should a shocked patient initially be managed?

A
  • Protect airway and NBM
  • two Cannula
  • All bloods, cross match 6 units
  • High flow 02
  • Rapid fluid infusion
  • if remains shocked, give blood?
  • Correct clotting abnormalities
  • Set up CVP line
  • Catheterise
  • Monitor
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6
Q

How should patients be transfused according to NICE?

A
  • Transfuse patients with massive bleeding with blood, platelets and clotting factors in line with local protocols for managing massive bleeding.
  • Base decisions on blood transfusion on the full clinical picture, recognising that over-transfusion may be as damaging as under-transfusion.
  • Do not offer platelet transfusion to patients who are not actively bleeding and are haemodynamically stable.
  • Offer platelet transfusion to patients who are actively bleeding and have a platelet count of less than 50 x 109/litre.
  • Offer prothrombin complex concentrate to patients who are taking warfarin and actively bleeding
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7
Q

When should endoscopy take place?

A
  • Offer endoscopy to unstable patients with severe acute upper gastrointestinal bleeding immediately after resuscitation.
  • Offer endoscopy within 24 hours of admission to all other patients with upper gastrointestinal bleeding.
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8
Q

What endoscopic treatment can be used in non variceal bleeding?

A

a mechanical method (for example, clips) with or without adrenaline

thermal coagulation with adrenaline

fibrin or thrombin with adrenaline.

DO not use adrenaline as monotherapy

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9
Q

When should PPIs be offered to patients with non variceal bleeding?

A

If stigmata of recent hemorrhage shown on endoscopy- not before

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10
Q

How should Variceal (of any type) Bleeding be Managed?

A
  • Offer terlipressin to patients with suspected variceal bleeding at presentation. Stop treatment after definitive haemostasis has been achieved, or after 5 days, unless there is another indication for its use
  • Offer prophylactic antibiotic therapy at presentation to patients with suspected or confirmed variceal bleeding.eg cipro 1g/24hr
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11
Q

How should oesophageal variceal bleeding be definitively managed?

A
  • Band Ligation
  • Consider TIPS if bleeding is not controlled by band ligation
  • Balloon tamponade can be used if failure of band
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12
Q

How should gastric varices be treated?

A
  • Offer endoscopic injection of N-butyl-2-cyanoacrylate

- Offer TIPS if bleeding not controlled by injection

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13
Q

How should patients on NSAIDs, Asprin or clopidogrel be managed?

A
  • Continue low dose aspirin for secondary prevention of vascular events if haemostasis achieved
  • Stop other NSAIDS during the acute phase
  • Discuss clopidogrel with pt and specialist
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14
Q

What happens to Urea in GI BLeed?

A

Goes up

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15
Q

What care is needed after endoscopy?

A
  • Omeprazole can prevent rebleeds
  • NBM 24hr then progress to clear fluid and light diet
  • Test for HPylori if ulcer
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16
Q

What are indications for surgery?

A
  • Rebleeding
  • Bleeding despite transfusing 6u
  • Uncontrollable bleeding at endoscopy
  • INitial rockall score >3 or total >6
17
Q

What maintenance therapy is needed after resus in GI Bleed?

A

Crystalloid IVI, transfuse if necessary (keep Hb≥10)
 Catheter + consider CVP (aim for >5cm H2O)
 Correct coagulopathy: vit K, FFP, platelets
 Thiamine if EtOH
 Notify surgeons of severe bleeds

18
Q

What are the important things to ask in Hx in GI Bleed?

A
  • Previous Bleeds
  • Dyspepsia or known ulcer
  • Liver disease, Known Varices
  • Alcohol
  • Comorbidities
  • Dysphagia/ wt. loss
19
Q

What may you find O/E in GI Bleed?

A
  • Signs of chronic Liver disease
  • Melaena on PR
  • Signs of Shock (low BP, HIgh HR, Low urine, Cap refil slow, Dec. GCS, Post drop)
20
Q

What are the common Causes of GI Bleed?

A

Common to Rare:

  • Peptic Ulcer Disease (DU common)
  • Gastritis/erosions
  • Mallory Weiss Tear
  • Varices
  • Oesophagitis
  • Gastric CA/Oesophageal CA
21
Q

What is a Rockall Score?

A

Prediction of bleeding and mortality- 40% of rebleeders die

22
Q

What is in the initial Rockall Score?

A

-Age
-Shock
-Comorbidities
>3 indication for surgery

23
Q

What is the post endoscopic ROckall Score?

A

-Final Diagnosis
-Evidence of recent haemorrhage
(out of 11 now)
>6 indicates surgery

24
Q

What are oesophageal Varices?

A

Portal HTN leads to dilated veins at points of porto-systemic anastamosis- L. Gastric and inferior Oesophageal Veins
-30-50% with portal HTN will bleed from varices

25
Q

what mortality is associated with variceal bleeds?

A

25%- increasing w/ severity of Liver disease

26
Q

Causes of portal HTN?

A

Pre Hepatic: Portal Vein Thrombosis
Hepatic: Cirrhosis (80% UK), Schisto (common worldwide), Sarcoidosis
Post Hepatic: Budd Chiari, RHF

27
Q

How can bleeds be prevented?

A

1o- Repeat endoscpoic banding, B-Blockers

-2o- Ditto and TIPS

28
Q

What is TIPSS?

A

-artificial channel between hepatic vein and
portal vein → ↓ portal pressure.
-Colapinto needle creates tract through liver
parenchyma which is expand using a balloon and
maintained by placement of a stent.
-Used prophylactically or acutely if endoscopic therapy
fails to control variceal bleeding.

29
Q

What is a blatchford Score?

A

-screening tool to assess the likelihood that a patient with an acute upper gastrointestinal bleeding (UGIB) will need to have medical intervention such as a blood transfusion or endoscopic intervention

30
Q

What is involved in blatchford score?

A

Score is 0 if:
Hemoglobin level >12.9 g/dL (men) or >11.9 g/dL (women)
Systolic blood pressure >109 mm Hg
Pulse <100/minute
Blood urea nitrogen level <6.5 mg/dL
No melena or syncope
No past or present liver disease or heart failure

31
Q

How would decompensated liver disease alter your management?

A

Avoid 0.9% NS in uncompensated liver disease (worsens
ascites). Use blood or albumin for resus and 5% dex for
maintenance