3. Resting Membrane Potential Flashcards
What is the normal resting membrane potential for nerve cells?
-75mV
What is the normal resting membrane potential for cardiac/skeletal muscle cells?
-90mV
Opening K+ or Cl- channels does what to the cell membrane potential?
Hyperpolarisation
Opening Na+ or Ca2+ channels causes what to the cell membrane potential?
Depolarisation.
What are the three types of gating?
Voltage
Ligand
Mechanical
Give two examples of excitatory transmitters
Acetyl Choline
Glutamate
Give two examples of inhibitory transmitters
Glycine
GABA
Slow synaptic transmission uses what type of receptor?
GPCR
Which protein is responsible for setting up and maintaining the ionic gradients needed to establish a membrane potential?
Na+K+ATPase
What sets up the resting membrane potential?
Mainly the outwards diffusion of K+ but fluttering and leaking of Na+, Cl- and Ca2+ can contribute