3. Indapamide Flashcards
1
Q
drug class
A
thiazide-like diuretic
2
Q
What is it used for?
A
hypertension.
3
Q
Mechanism of action
A
• Inhibit N+/Cl- co-transporter in distal convoluted tubule - ↓Na+ and H2O reabsorption
4
Q
Important adverse drug reactions
A
Hypokalaemia, hyponatraemia, hyperuricemia (gout), arrhythmia
↑glucose (especially with beta-blockers)
small ↑cholesterol and triglyceride
5
Q
Important drug-drug interactions
A
Hypokalaemia, hyponatraemia, gout
6
Q
warnings, contraindications
A
NSAIDs, ↓K+ drugs such as loop diuretics (electrolyte monitoring required)
7
Q
why do you think it is recommended that this drug is taken first thing in the morning and not before bed?
A
might cause nocturia if taken at night
