3. digestion fact test Flashcards

1
Q

what is the role of the mouth in the digestive system

A

carries out
physical breakdown (chewing by teeth which increases surface area)
chemical digestion (salivary amylase)

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2
Q

what is the role of the oesophagus in the digestive system

A

transports food (bolus) from mouth to stomach, facilitated by a wave of muscle contraction

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3
Q

what is the role of the stomach in the digestive system

A

carries out physical breakdown (contraction of muscular walls to churn the food), temporarily stores food, carries out chemical digestion (glands release proteases) and contains hydrochloric acid

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4
Q

what is the role of the liver in the digestive system

A

produces bile which contains bile salts. these facilitate lipid digestion due to emulsification

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5
Q

what is the role of the pancreas in the digestive system

A

secretes pancreatic juice into small intestine
juice contains proteases, lipases and pancreatic amylase
the juices are alkaline to help create optimum pH in ileum

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6
Q

what is the role of the large intestine (colon) in the digestive system

A

absorbs excess water and ions, contains a plethora of bacteria which produce certain vitamins

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7
Q

what is the role of the rectum in the digestive system

A

stores compacted, indigestible material (faeces) before it is removed from the body via the anus

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8
Q

what happens in the small intestine (ileum) in the digestive system

A

where chemical digestion and absorption of soluble food molecules takes place

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9
Q

how is the small intestine adapted to its functions

A
  • villi and microvilli provide a very large surface area for diffusion of food molecules
  • epithelium is one cell thick for reduced diffusion distance
  • muscle in villi allows movement and increased contact with food molecules
  • rich blood supply to maintain diffusion gradient
  • lacteals to allow lipid transport
  • epithelial cells have many mitochondria to produce ATP and co-transport proteins for active transport
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10
Q

what is physical digestion

A

breaking down large food molecules into smaller pieces, increases surface area for chemical digestion

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11
Q

what is chemical digestion

A

hydrolysis of large insoluble molecules into smaller soluble ones, completed by enzymes

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12
Q

what do endopeptidases do

A

hydrolyse peptide bonds between amino acids in central region of a protein molecule forming a series of peptide molecules

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13
Q

what do exopeptidases do

A

hydrolyse peptide bonds on the terminal amino acids of peptide molecules

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14
Q

what do dipeptidases do

A

hydrolyse bond between 2 amino acids of a dipeptide

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15
Q

what enzymes are involved in lipid digestion

A

lipase

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16
Q

where is lipase made and where does it work

A

made in pancreas
works in small intestine

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17
Q

what is the substrate which binds to the lipase

A

triglyceride

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18
Q

what is the product formed after lipase action

A

fatty acids and monoglycerides

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19
Q

what enzymes are involved in protein digestion

A

endopeptidases
exopeptidases
dipeptidases

20
Q

where are endopeptidases made and where do they work

A

made in stomach and pancreas
work in stomach and small intestine

21
Q

what substrate binds to endopeptidases

A

polypeptides

22
Q

what product is formed from endopeptidase action

A

short chain polypeptides

23
Q

where is exopeptidase made and where does it work

A

made in pancreas
works in small intestine

24
Q

what is the substrate that binds to exopeptidases

A

polypeptides

25
Q

what product is formed from exopeptidase action

A

shorter chain polypeptides

26
Q

where is dipeptidase made and where does it work

A

epithelium of small intestine (membrane-bound)

27
Q

what is the substrate which binds to dipeptidases

A

dipeptides

28
Q

what is the product of dipeptidase action

A

amino acids

29
Q

what enzymes are involved in carbohydrate digestion

A

salivary amylase
pancreatic amylase
maltase
sucrase
lactase

30
Q

where is salivary amylase made and where does it work

A

made in salivary glands
works in mouth

31
Q

what substrate binds to salivary amylase

A

starch

32
Q

what is the product of salivary amylase action

A

maltose

33
Q

where is pancreatic amylase made and where does it work

A

made in pancreas
works in small intestine

34
Q

what is the substrate that binds to pancreatic amylase

A

starch

35
Q

what is the product of pancreatic amylase action

A

maltose

36
Q

where is maltase made and where does it work

A

epithelium of small intestine (membrane-bound)

37
Q

what is the substrate which binds to maltase

A

maltose

38
Q

what product is formed from maltase action

A

glucose

39
Q

where is sucrase made and where does it work

A

epithelium of small intestine

40
Q

what is the substrate that binds to sucrase

A

sucrose

41
Q

what are the products formed from sucrase action

A

glucose and fructose

42
Q

where is lactase made and where does it work

A

epithelium of small intestine

43
Q

what substrate binds to lactase

A

lactose

44
Q

what are the products formed from lactase action

A

glucose and galactose

45
Q

what is the process of the absorption of lipids

A
  • large lipid droplet is emulsified by bile, creating smaller fat droplets. this creates a larger surface area for lipase to hydrolyse triglycerides into fatty acids and monoglycerides
  • they form micelles with bile salts
  • micelles come into contact with epithelial cells lining villi of ileum. micelles release monoglycerides and fatty acids. fat soluble components diffuse into epithelial cell leaving behind fat insoluble bile salts
  • once inside epithelial cell, monoglycerides and fatty acids are transported to smooth endoplasmic reticulum where they are recombined to form triglycerides
  • triglycerides are transported in vesicles to golgi apparatus where they associate with cholesterol and proteins to form chylomicrons
  • chylomicrons move out of epithelial cells via exocytosis. they enter lymphatic capillaries called lacteals that are found in the center of the villi and eventually enter the bloodstream