3: Derm 1 Flashcards
What causes hand foot and mouth dz?
Coxsackievirus A16
Enterovirus 70
What are the complications of early stage lyme dz?
Fever, fatigue, malaise, headache, neck/joint stiffness (myalgias/arthralgias), lyme meningitis
Subclass of cellulitis that is superficial with sharp, defined borders caused by GABHS.
Erysipelas
What is treatment for measles?
Supportive
Avoid ASA
What is the treatment for neurologic lyme dz (2)?
- Ceftriaxone 2 g once daily IV x 14 days (range 10-28 days)
- Doxy 200-400 mg/day in 2 divided doses PO x 10-28 days if intolerant to beta-lactam ABX
What are the complications of early disseminated lyme dz?
Multiple erythema migrans (3–5 weeks after bite), facial palsy, aseptic meningitis, cardiac involvement (AV block and myocarditis), musculoskeletal pain
What can fifth’s dz cause in a pregnant woman?
Hydrops fetalis
Organism that causes Lyme disease.
Borrelia burgdorferi spirochete
What diameter is the target rash in lyme dz?
5-15 cm
When is vaccination for meningococcemia done?
Age 11 and before starting college.
Ages 2-5 for certain high-risk children.
Erythematous papule/pustule around a hair follicle.
Folliculitis
T/F Scarlet fever requires rapid strep test or throat culture.
True (caused by same organism)
DDx of shingles?
HSV
Impetigo
A mild illness also known as German measles.
Rubella
Where does staph scalded skin syndrome usually start?
Respiratory site such as nose or mouth
Reactivation of latent varicella infection that is more common after a mild case of chickenpox.
Shingles
What are transmission routes for hand foot and mouth?
Fecal
Oral
Respiratory
Manifests as a subcorneal pustule with erosions and honey-colored crusts
Impetigo
How is rubella acquired?
Respiratory secretions. Invades respiratory epithelium.
What is the treatment for hand foot and mouth?
Symptomatic. May require tylenol or benadryl/maalox solution for oral lesions (can use non-salicylate antacid if concerned for salicylates).
What animals/rodents carry the lyme spirochete?
Deer
Rodents (white tailed mouse)
Ticks
When does varicella occur?
Late autumn, spring, and winter
What is staph scalded skin syndrome called in neonates?
Ritter’s disease
What is the medication treatment for impetigo (6)?
- Beta lactamase-resistant penicillin or cephalosporin for 5–10 days
- Oral if sick. Topical if not sick.
- Mupirocin (Bactroban) TID for 5–10 days
- Altabax (retapamulin)
- Bleach baths
- Penicillin alternatives: erythromycin and clarithromycin
May follow a break in the skin caused by nail biting or tearing a hangnail.
Acute paronychia
Clinical manifestions: low-grade fever, HA, chills, followed by erythematous facial rash, and lacy, maculopapular rash
Fifth’s dz
What is the prevention for rubella?
May give IG for pregnant, nonimmunized, exposed women.
MMR vaccine at 12 months and 4 years old.
Vaccine for postpartum women if not immune during pregnancy.
Localized skin infection, involving dermis and subcutaneous tissue with obstruction of local lymphatics.
Cellulitis
Chronic paronychia causes inflammation and edema without _____.
Pain
T/F Cellulitis can be associated with fever, chills, and malaise.
True
Rubbing erythematous skin sideways causes superficial epidermis to slough off.
Nikolsky’s sign (staph scalded skin syndrome)
In meningococcemia, leakage of the endotoxin in the bacterial cell walls can cause what (3)?
DIC
Irreverisible shock
Multisystem failure
Treatment for chronic paronychia (2).
- Antifungals
2. Antibiotics
What is the treatment for staph scalded skin syndrome?
- ICU
2. Systemic antistaph ABX
What is the treatment for rubella?
Supportive
Name 3 sequelae of scarlet fever.
- Rheumatic fever
- Heart problems
- Acute glomerulonephritis
Treatment for cellulitis.
- Outpatient oral antibiotics (Keflex [cephalexin], Augmentin [amoxicillin/clavulanate]) for early onset cellulitis
- Consider coverage for MRSA
- Follow up closely to watch for sepsis
Upper respiratory prodrome followed by high fever, chills, headache, toxicity, and hypotension.
Meningococcemia
Caused by circulating staph toxin which can exfoliate the skin.
Staph scalded skin syndrome
Staph scalded skin syndrome can be related to _____ if no peeling.
nonstrep scarlet fever
What is a complication of fifth’s dz?
Aplastic anemia (esp for those with sickle cell or pregnant women)
What are long term complications of lyme dz?
Chronic arthritis
Neurological sequelae
How is rubella diagnosed?
Viral isolates from nasopharyngeal secretions
10 complications of impetigo.
- Sepsis
- Arthritis
- Pneumonia
- Lymphadentitis
- Toxic shock
- Osteomylitis
- Endocarditis
- Cellulitis
- Staph scalded skin syndrome
- APSGN (Acute poststreptococcal glomerulonephritis)
What is incubation period for varicella?
10-21 days (mean 14 days)
What is the prophylaxis for lyme dz?
Tests not necessary.
Single dose of doxy (200 mg for adults, 4 mg/kg for children >8 with max of 200)
Ill, miserable child with dusky red maculopapular rash on face that spreads to trunk. Rash lasts 7-10 days, but brown macules can last u to 3 weeks.
Measles
Organism that causes meningococcemia.
Neisseria meningitidis
What is the treatment for meningococcemia?
High dose penicillin G q 4-6 hours
Alternatives are cefotaxime, ceftriasone, and chloramphernicol
Describe the 2 phases of staph scalded skin syndrome.
- Prodromal phase - Bright erythema around mouth, fever, irritability
- Exfoliative phase - Tender, inflamed peeling skin. Red oral mucosa. Peeling on trunk.
T/F Rubella has a periodic occurrence of wintertime epidemics.
False. Springtime.
Resembles impetigo but extends through to dermis.
Ecthyma