3. Cardiomyopathies

Question 1

Cardiomyopathy

Answer 1

Heart muscle is structurally and functional abnormal in the absence of coronary artery disease and hypertension

Question 2

Categories based on morphology and physiology

Answer 2

Dilated - dilation and abnormal contraction of one or both ventricles, cause:idiopathic /genetic
abnormal contractility, systolic dysfunction

Hypertrophic - hypertrophy of LV, cause: genetic, hypertrophy
abnormal compliance, diastolic dysfunction

Restrictive - non-dilated ventricles, cause: myocardial fibrosis
abnormal compliance, diastolic dysfunction

Question 3

LVEF of functional levels of cardiomyopathy

Answer 3

Dilated - Less than 40%
Hypertrophic- 50-80%
Restrictive - non-dilated ventricles

Question 4

Dilated cardiomyopathy

Answer 4

Spectrum of heterozygous myocardial disorders that are characterized by ventricular dilation and decrease in cardiac output

Pathogenesis of HF related to DCM

1. Ischemic - caused by ischemic heart disease
2. Non-ischemic cardiomyopathy (DCM)