3 - Cardiomyopathies Flashcards
What is the second MC cause of SCD in teens and the leasing cause of death in competitive athletes?
Hypertrophic cardiomyopathy
The primary cardiomyopathies:
Slide 7 long list
Common causes of secondary cardiac myopathies
Slide 8 - long list
Clinical features and ECG for dilated cardiomyopathy?
Congestive heart failure
Chest pain
Regurgitant murmurs
LVH, poor R-wave progression
Clinical features and ECG for myocarditis?
Fever
Tachycardia
Myalgias
CP
Nonspecific ST-T wave changes, often with pericarditis
Clinical features and ECG for HOCM
DOE CP Palpitations Syncope Prominent J wave Pulsus bisferiens Systolic ejection murmur (increases with valsalva and decreases with squatting)
LVH, large septal Q waves
Usual cause of dilated cardiomyopathy?
Idiopathic
What is the primary indication for cardiac transplant in the US?
Dilated cardiomyopathy
Risks for dilated cardiomyopathy
black, male, age 20-50
Majority have advanced dz by the time of presentation
Describe dilated cardiomyopathy?
Systolic and diastolic dysfunction and diminished LV and RV contractile force, resulting in low CO and increased end-systolic and end-diastolic ventricular volumes
Hallmarks of dilated cardiomyopathy?
LV (and often RV) dilation accompanied by normal LV wall thickness
Sxs of dilated cardiomyopathy?
Looks like CHF
DOE Orthopnea PND Bibasilar rales Dependent edema
Why CP with dilated cardiomyopathy?
Limited coronary vascular reserve rather than atherosclerotic dz
Clinical features of dilated cardiomyopathy
Impaired valve closure
Holosystolic mitral or tricuspid regurgitant murmurs at LLSB
Enlarged liver and pulsatile if tricuspid insufficiency is significant
Dx of dilated cardiomyopathy?
Not usually made in the ED
Typically made at follow-up via echo
CXR with dilated cardiomyopathy
Enlarged cardiac silhouette and increased cardiothoracic ratio
MC findings on ECG for dilated cardiomyopathy?
LV hypertrophy and left atrial enlargement
Also, a-fib is common
How urgent is the echo with dilated cardiomyopathy?
Driven by patient presentation
Get it when:
Cause of HF is uncertain
To exclude known causes of HF that may be correctable
To estimate ejection fraction
To R/O other potential complications that may be amenable to therapy
What improves pt survival in cardiomyopathy pts?
ACE inhibitors
Blockers
Carvedilol
Dilated cardiomyopathy pts with ventricular ectopy may benefit from:
Amiodarone
Implanted pacemaker defibrillator
ED txt for dilated cardiomyopathy 2/2 noncompliance
Nitrates
IV diuretics
Re-start normal meds
Patient counseling
Make sure you r/o severe issues, as well (i.e. possible ischemia)
LVAD?
Awesome and weird device for severe dilated cardiomyopathy patients - moves the blood for em
Hallmarks of HCM?
On echo -> asymmetric septal hypertrophy and histologic hypertrophy associated with myocardial fiber disarray surrounding areas of increased loose CT
Describe the hemodynamics of HCM
Abnormal LV diastolic dysfunction d/t reduced compliance of the hypertrophied left ventricle
In HCM, decreased compliance is reflected by:
Increase in LV filling pressure
Most frequent complaint associated with HCM?
DOE 2/2 exercise-induced sinus tach
Why CP in HCM?
Imbalance between o2 demand of hypertrophied LV and the available myocardial blood flow
How do HCM pt’s respond to NTG?
Poorly - highly variable
Bc its a problem with the heart structure, not vessel issues
During a HCM episode, pt’s may complain of:
Palpitations d/t forceful ventricular contractions
Is JVP elevated in HCM pts?
Nope (not usually)
In most patients with HCM, cardiac exam will reveal
S4
Where is the systolic ejection murmur of HCM best heard?
LLSB or at the apex
Maneuver to accentuate the murmur of HCM
Standing
Valsalva
Maneuver to decrease the HCM murmur
Squatting
Passive leg elevation
Hand grip
*things that increase LV filling
Effective bedside interventions on the murmur of HCM vs mitral valve prolapse
Chart - slide 33
*YOU NEED TO KNOW THIS
DX of HCM
Echo to confirm
ECG - LVH and LAE, disproportionate septal hypertrophy
If the HCM pt experiences syncope:
They’re getting admitted
Mainstay therapy for CP in pt’s with HCM:
B-blockers
Slow that HR down
Common causes of acute pericarditis:
Slide 40
KNOW THIS
Normal amt of pericardial fluid
50ml
MC symptom of acute pericarditis
Sharp, stabbing precordial or retrosternal CP
Sxs of acute pericarditis
Pericardial friction rub (hard to hear)
Sudden or gradual onset
Radiating pain, aggravated by inspiration or movement
Pain more severe when supine, relieved when sitting up and leaning forward
Fever, dyspnea
Stages of pericarditis
Slide 43 - know this
Low-voltage QRS and electrical alternans suggests:
Development of large pericardial effusion
Procedure of choice for acute pericarditis detection, dx, and follow-up:
Echocardiography
Txt of acute pericarditis
Most resolve on their own
Ibuprofen 300-800mg’s every 6-8 hrs
Colchicine 0.5mg PO BID
Which pericarditis pts am i admitting ?
>100.4 Subacute onset over weeks Immunosuppressed Hx of oral anticoagulant use Associated myocarditis Large pericardial effusion (>20mm)
Whats the big problem with cardiac tamponade?
Barney answer - prevents filling
Factors that determine the rate at which tamponade occurs?
- Rate of fluid accumulation
- Pericardial compliance
- Intravascular volume
Common causes of nontraumatic cardiac tamponade:
Metastatic malignancy (MC)
Acute Idiopathic pericarditis
Uremia
Bacterial or tubercular pericarditis
Chronic idiopathic pericarditis
Hemorrhage (anticoagulant use)
Possible findings with the cardiac tamponade patient
Pulsus paradoxus
JVD
Absent “y” descent
Strong apical impulse
“Distant” heart sounds on auscultation
ECG for cardiac tamponade
Electrical alternans is classic but uncommon…whatever the fuck that means…
Low voltage QRS complexes with PR-depression
TOC for cardiac tamponade?
Echocardiography
Dx of cardiac tamponade should be suspected based on:
Clinical exam and chest radiograph findings
Confirmed with echo
Txt for cardiac tamponade
Volume expansion with a bolus of saline (1/2 to 1 L) - temporary measure
Pericardiocentesis is necessary for definitive therapy AND specific Dx
Admit your cardiac tamponade pt if:
Hemodynamically unstable
Or
You did an emergent
Pericardiocentesis
Or
Pt has insufficient social situation to provide access to emergency care
What is Beck’s triad?
JVD
HOTN
Muffled heart sounds
Think “cardiac tamponade”
According to a new study marijuana users are twice as likely to suffer from a heart condition known as stress cardiomyopathy
But they’re three times as likely not to care