3-3 Digestion and absorption Flashcards

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1
Q

What is digestion?

A
  • The hydrolysis of large biological molecules into smaller molecules which can be absorbed across cell membranes.
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2
Q

How are carbohydrates digested?

A
  • Carbohydrates are digested by many different enzymes.
  • Amylases in the mouth digest larger polymers
  • Maltase’s in the ileum break down monosaccharides
  • Sucrases break down sucrose
  • Lactose breaks lactose
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3
Q

How are lipids digested?

A
  • Lipids are digested by lipases which hydrolyse the ester bond between the monoglycerides and fatty acid.
  • Before being broken down in the ileum, lipids are emulsified int micelles by bile salts released by the liver.
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4
Q

What is the purpose of emulsification in lipid digestion?

A
  • Emulsification increases the surface area and speeds up the chemical reaction.
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5
Q

How are proteins digested?

A
  • Proteins are digested by enzymes called peptidases of which they are divided into 3 main groups.
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6
Q

What are the 3 main peptidase groups?

A
  • Endopeptidases, hydrolyse peptide bonds between specific amino acids in the middle of a polypeptide.
  • Exopeptidases, hydrolyse bonds at ends of polypeptides.
  • Dipeptidases, break dipeptides into individual amino acids.
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7
Q

What happens to the products of digestion?

A
  • Absorbed by cells lining the ileum of mammals.
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8
Q

What happens to amino acids after digestion?

A
  • Amino acids are absorbed by facilitated diffusion through specific carrier molecules in the surface membrane of epithelial cells.
  • With each amino acid, on Na+ is also taken up, therefore amino acid absorption occurs via a process known as co-transport.
  • A diffusion gradient for Na+ is maintained by their active transport through the base of epithelial cells where amino acids pass by facilitated diffusion.
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9
Q

What happens to monoglycerides and fatty acids after digestion?

A
  • Monoglycerides and fatty acids are polar so they can easily diffuse across the cell membrane into the epithelial cells lining the epithelium.
  • Once inside they are transported to the endoplasmic reticulum where they are reformed into triglycerides again.
  • After this they move out of the cells by vesicles into the lymph system.
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