2pqs Flashcards
A 62-year-old man with advanced non-small cell lung cancer begins a chemotherapy regimen involving a platinum-based agent known for its efficacy in treating his condition. During a follow-up visit, he mentions new symptoms affecting his daily activities, prompting further evaluation by his oncologist.
What side effect is most likely associated with this patient’s treatment?
cisplatin may cause peripheral neuropathy. Commonly used in NSCLC
Three days after receiving cisplatin, she develops reduced urine output. On examination, she appears dehydrated with dry mucous membranes. management? egfr of 29
Administer intravenous fluids with magnesium supplementation is the correct management for this patient who is showing clear signs of cisplatin-induced nephrotoxicity with concurrent hypomagnesaemia. Cisplatin is well-known for causing dose-dependent nephrotoxicity, which is its primary dose-limiting side effect.
lab finding in bone pain, anaemia, and hypercalcaemia presenting as nephrolithiasis (haematuria and colicky pain).
Low PTH levels
The patient likely has multiple myeloma suggested by bone pain, anaemia, and hypercalcaemia presenting as nephrolithiasis (haematuria and colicky pain). In multiple myeloma, hypercalcaemia results from osteolytic bone destruction, which releases calcium from bones into the bloodstream. The resultant hypercalcaemia suppresses PTH production through negative feedback, leading to low PTH levels.
most common primary malignant brain tumour in adults and typically presents
Glioblastoma is the most common primary malignant brain tumour in adults and typically presents with progressive neurological symptoms and imaging findings of an irregular lesion with oedema.
