2nd Shifting LQ Flashcards
Neoplasms Kidney Male GT
most common forms of antibody mediated glomerulonephritis
Immune complex formation
most common benign tumor
leiomyoma
2 major histologic characterisitic of proggressive renal damage
- Focal Segmental Glomerulonephritis
2. tubulointerstitial Fibrosis
describe nephritic syndrome
azotemia, proteinuria, HTN
Describe nephrotic syndrome
> 3.5gm Proteinuria
hypoalbuminemia
anasarca
inc. lipid. lipiduria
most common cancer malignancy leading to death
Lung CA
Most important primary glomerular disease
MCD
FSGN
Membranous glomerulopathy
most common malignancy in males
prostate CA
most common malignancy in females
breast CA
most common cause of nephrotic syndrome to children
Minimal Change Disease
most common tumor to secondarily involve prostate CA
Urothelial CA
control glomerular permeability; key component of slit diaphragm
nephrin
most aggressive prostate CA form
Small Cell CA
most common type of glomerulonephritis worlwide
IgA Nephropathy aka Berger’s Disease
most common benign prostatic disease >50y/o
BPH
2nd most common cause of acute kidney injury
Drug-induced tubulointerstiitial nephritis
most common testicular tumor in >60y/o
NON-Hodgkin’s lymphoma
most common cause of Renal Artery Stenosis
Atheromatous plaque->renal artery-> narrowing of origin
most common cause of painless testicular enlargement
testicular germ cell tumor
2nd most common cause of RAS
Fibromuscular Dysplasia
most common testicular tumor in infants, child = 3 y/o
Yolk Sac tumor
most common type of Renal CA (70-80%)
Clear Cell Carcinoma
most of germ cell tumors come from?
Intratubular Germ Cell Neoplasia (ITGCN)
most common cause of hydronephrosis in infants and children
Uteropelvic junction obstruction
mo st common form of germ cell tum or
seminomas
most common form of hydronephrosis in children
bilateral?unilateral?
bilateral
most common primary congenital bladder anomaly
vesicoureteral reflux
common malignant paratesticular tumor in
Child?
Adult?
Child: rhabdomyosarcoma
Adult: liposarcoma
most often cause of bladder obstruction
cystocele
most common benign paratesticular tumor
adenomatoid
common cause of phimosis
balanoposthitis
most common site of arrest in BPH
inguinal canal
etiologic agents in epididymitis,orchitis in:
<35 y/o?
>35y/o?
<35 y/o: C. Trachomatis, N. gonorrhea
>35y/o? E.Coli, Pseudomonas
serum tumor marker for hepatocellular CA
AFP
CEA is for CA in what organs?
Pancreas, Colon, Breast, Lungs, Stomach
serum tumor marker for pancreatic adenocarcinoma
CA19-9
serum tumor marker for malignant ovarian epithelial tumor
CA-125
hallmarks of CA
- self-sufficiency in growth signals
- insensitivity to growth inhibitory signals
- limitless replicative capacity
- evasion of apoptosis
- sustained angiogenesis
- invasion & metastasis
- evade immune response
- Wargburg effect