2nd Shifting LQ Flashcards

Neoplasms Kidney Male GT

1
Q

most common forms of antibody mediated glomerulonephritis

A

Immune complex formation

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2
Q

most common benign tumor

A

leiomyoma

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3
Q

2 major histologic characterisitic of proggressive renal damage

A
  1. Focal Segmental Glomerulonephritis

2. tubulointerstitial Fibrosis

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4
Q

describe nephritic syndrome

A

azotemia, proteinuria, HTN

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5
Q

Describe nephrotic syndrome

A

> 3.5gm Proteinuria
hypoalbuminemia
anasarca
inc. lipid. lipiduria

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6
Q

most common cancer malignancy leading to death

A

Lung CA

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7
Q

Most important primary glomerular disease

A

MCD
FSGN
Membranous glomerulopathy

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8
Q

most common malignancy in males

A

prostate CA

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9
Q

most common malignancy in females

A

breast CA

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10
Q

most common cause of nephrotic syndrome to children

A

Minimal Change Disease

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11
Q

most common tumor to secondarily involve prostate CA

A

Urothelial CA

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12
Q

control glomerular permeability; key component of slit diaphragm

A

nephrin

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13
Q

most aggressive prostate CA form

A

Small Cell CA

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14
Q

most common type of glomerulonephritis worlwide

A

IgA Nephropathy aka Berger’s Disease

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15
Q

most common benign prostatic disease >50y/o

A

BPH

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16
Q

2nd most common cause of acute kidney injury

A

Drug-induced tubulointerstiitial nephritis

17
Q

most common testicular tumor in >60y/o

A

NON-Hodgkin’s lymphoma

18
Q

most common cause of Renal Artery Stenosis

A

Atheromatous plaque->renal artery-> narrowing of origin

19
Q

most common cause of painless testicular enlargement

A

testicular germ cell tumor

20
Q

2nd most common cause of RAS

A

Fibromuscular Dysplasia

21
Q

most common testicular tumor in infants, child = 3 y/o

A

Yolk Sac tumor

22
Q

most common type of Renal CA (70-80%)

A

Clear Cell Carcinoma

23
Q

most of germ cell tumors come from?

A

Intratubular Germ Cell Neoplasia (ITGCN)

24
Q

most common cause of hydronephrosis in infants and children

A

Uteropelvic junction obstruction

25
Q

mo st common form of germ cell tum or

A

seminomas

26
Q

most common form of hydronephrosis in children

bilateral?unilateral?

A

bilateral

27
Q

most common primary congenital bladder anomaly

A

vesicoureteral reflux

28
Q

common malignant paratesticular tumor in
Child?
Adult?

A

Child: rhabdomyosarcoma
Adult: liposarcoma

29
Q

most often cause of bladder obstruction

A

cystocele

30
Q

most common benign paratesticular tumor

A

adenomatoid

31
Q

common cause of phimosis

A

balanoposthitis

32
Q

most common site of arrest in BPH

A

inguinal canal

33
Q

etiologic agents in epididymitis,orchitis in:
<35 y/o?
>35y/o?

A

<35 y/o: C. Trachomatis, N. gonorrhea

>35y/o? E.Coli, Pseudomonas

34
Q

serum tumor marker for hepatocellular CA

A

AFP

35
Q

CEA is for CA in what organs?

A

Pancreas, Colon, Breast, Lungs, Stomach

36
Q

serum tumor marker for pancreatic adenocarcinoma

A

CA19-9

37
Q

serum tumor marker for malignant ovarian epithelial tumor

A

CA-125

38
Q

hallmarks of CA

A
  1. self-sufficiency in growth signals
  2. insensitivity to growth inhibitory signals
  3. limitless replicative capacity
  4. evasion of apoptosis
  5. sustained angiogenesis
  6. invasion & metastasis
  7. evade immune response
  8. Wargburg effect