295 Mech Vent Flashcards
Chap 295 Mechanical Ventilatory Support
Primary indication for initiation of MV
Respiratory failure
Two types of Respiratory failure
Hypoxemic
Hypercarbic
Respiratory failure that presents when arterial O2 saturation is less than 90% despite increased inspired O2 fraction and usually results form ventilation perfusion mismatch or shunt
Respiratory failure type 1 hypoxemic
Respiratory failure that is characterized by elevated arterial carbon dioxide pressure of more than 50 mmHg decreasing minute ventilation or increase physiologic dead space
Respiratory failure Type 2 hypercarbic
Most common reason for instituting MV which accounts for 65% Examples
Acute Respiratory failure with hypoxemi
Examples: ARDS, heart failure with pulmonary edema, pneumonia, sepsis, complications of surgery or trauma
Causes of hypercarbic Respiratory failure
Coma
COPD in AE
Neuromuscular disease
Primary objective of MV
Decrease work of breathing
Avoid Respiratory muscle fatigue
Reverse life threatening hypoxemia and progressive Respiratory acidosis
Two basic methods of MV
NIV
Invasive ventilation
Most important group who benefit from trial of NIV
COPD exacerbations and Respiratory acidosis pH less than 7.35
Good clinical indicator of therapeutic benefit of NIV
Reduction in Respiratory rate
Decrease in use of accessory muscle (scalene, sternomastoid and intercostal)
Good choice for pre intubation sedation
Opiates and benzodiapines
Why is morphine not used as pre intubation sedation?
Morphine promote histamine release from tissue mast cells and may worsen bronchosoasn in patients
Acceptable alternatives to morphine pre intubation sedation
Fentanyl
Sufentanil
Alfentanil
Why is ketamine not used pre intubation sedation?
Increases arterial pressure and has been associated with hallucinatory response
Contraindications to NIV
Cardiac or Respiratory arrest Severe encephalopathy Severe GI bleed Hemodynamic instability Unable angina and myocardial infarction Facial surgery or trauma Upper airway obstruction High risk for aspiration or inability to protect airways Inability to clear secretions