273 DVT Flashcards
Focal oligemia
Westermark sign
Peripheral wedge shaped density located
Hamptons hump
Prominent descending right pulmonary artery
Palla sign
Principal imaging test for PE
CT chest with contrast. PE protocol
2nd diagnostic test for PE for patient with allergy to contrast
Lung scan
Hypokinesia of the RV free wall
Mc Connells Sign
Definitive diagnosis of PE
Visualization of an intra luminal filling defect in more than 1 projection; reserve is there is plan for thrombolysis
Whats the most common sign of PE and most common symptom of PE?
Sign: tachycardia, HR more than 100 bpm Symptoms: dypnea/ unexplained breathlessness
PE. RV hypokinesia + hypotension
Anticoagulation + thrombolysis; Embolectomy
3 strategies for DVT/PE treatment
- Parenteral anticoagulant with UF, LMWH, Fondaparinux bridged to warfarin
- Parenteral x 5 days then dabigatran/edoxaban
- Monotherapy with DOACs: rivaroxaban & apixaban
APTT target for UFH in DVT
APTT 60-80 secs
Why bridging therapy in warfarin in DVT
Warfarin has a early pro coagulant effect so overlap with UFH, LMWH
Direct factor Xa inhibitor approved for VTE without parenteral bridging anticoagulant
Rivaroxaban and apixaban
Best DOACs for patient with renal co morbidities
Apixaban. No need for renal adjustment
Duration of anticoagulation in DVT
Provoked: 3-6 months
Cancer: until cancer is no longer active
Unprovoked: indefinitely