26 Flashcards
what is the weight and size of the heart influenced by?
age gender body weight physical exercise heart disease
3 layers of the heart
endocardium myocardium epicardium
Blood flow through the heart
superior/inferior vena cave > R atrium > tricuspid valve > R ventricle > pulmonic valve > L pulmonary artery > Lungs > pulmonary veins > L atrium > mitral valve > L ventricle > aortic valve > aorta> Body https://www.khanacademy.org/science/health-and-medicine/human-anatomy-and-physiology/heart-introduction/v/flow-through-the-heart
Diastole
all chambers relax allowing ventricles to fill in preparation for contraction
systole
atrial and ventricular contraction
oxygenated vs. deoxygenated blood
deoxygenated blood from the R side of the heart is distributed to the lungs for oxygenation then oxygenated blood is returned to the L side of the heart
the pulsation, known as point of maximal impulse, created during normal ventricular contraction is _______ ________
apical impulse
_____ ______ is inadequate O2 supply
myocardial ischemia
_____ _____ ____ generates and transmits electrical impulses that stimulate contraction of the myocardium
cardiac conduction system
the conduction system stimulates the atria then ventricles. this allow ventricles to fill completely before ejection which maximizes _______ ______
cardiac output
electrical cells (nodal and purkinje cells) responsible for the electrical impulse of the atria and ventricle work by _________, _________, __________
automaticity excitability conductivity
_______ is the ability to initiate an electrical impulse
automaticity
_______ is the ability to respond to an electrical impulse
excitability
_______ is the ability to transmit an electrical impulse from one cell to another
conductivity
what is known as the primary pacemaker of the heart?
SA node
_____ _____ are responsible for supplying arterial blood to the heart
coronary arteries
electrical activation of a cell caused by influx of Na+ into the cell while K+ exits the cell is known as ___________
depolarization
____ ____ ___ is a rupture of an atheromatous plaque in a diseased coronary artery
acute coronary syndrome
return of cell to resting state caused by re-entry of K+ into the cell while Na+ exits is known as ____________
repolarization
phases of cardiac action potential
phase 0- rapid depolarization of atrial and ventricular myocytes, Na+ moves out of cell through fast channels, cells of SA/AV node depolarize when Ca+ enters cell through slow channels phase 1- early repolarization as K+ exit cell phase 2- plateau phase, repolarization slows down, Ca+ enters
phases of cardiac action potential
phase 3- return of resting state, completion of repolarization phase 4- resting phase before next depolarization
_____ ______ is the time which myocardial cells must completely repolarize before they depolarize again
refractory period
_____ refractory period is when the cell is unresponsive to any stimulus and incapable of depolarizing. related to phase 0 - middle of phase 3
effective
if a electrical stimulus is stronger than normal than _______ refractory period occurs and the cell may depolarize prematurely.
relative
early depolarization of the atrium or ventricular cause premature contractions and place the person at risk for ____________
dysrhythmias
______ ______ rhythm occurs when the electrical impulse starts at a regular rate and rhythm in the sinus node and travels through the normal conduction pathway
normal sinus (Legaspi said to know this, not sure if it is on test but its located in Ch 27)
Characteristics of normal sinus
ventricular/atrial rate: 60-100 ventricular/atrial rhythm: regular QRS shape and duration: normal or regularly abnormal P wave: normal and consistent shape, always in front of QRS PR interval: consistent interval b/w 0.12 and 0.20 seconds P: QRS ratio 1:1
______ ________ rapid irregular twitching of the muscular wall of the atria. common in ppl with hypertension/diabetes/structural heart disease/sleep apnea etc
atrial fibrillation
_______ ________ is disorganized rhythm that causes quivering of the ventricles. commonly caused by CAD and acute MI and there is no atrial activity seen on the ECG
ventricular fibrillation
3 or more premature ventricular complexes in a row more than 100 bpm result in a pt being unresponsive and pulseless. this is known as _______ ________
ventricular tachycardia
if a pt has absent cardiac activity with no heartbeat/pulse/ or respirations. this is known as _________ and can be fatal.
asystole
blood flows from an area of high pressure to low pressure and this is known as _______ _________. pressures responsible for blood flow in the normal circulation are generated during systole and diastole
cardiac hemodynamics
pumping action of the heart including systole and diastole is known as the ______ ________ and it occurs from one heart beat to the next
cardiac cycle https://www.youtube.com/watch?v=5tUWOF6wEnk
_____ _____ is the amount of blood pumped by each ventricle during a given period. the average is about 5 L/min in a resting adult
cardiac output
what can have an effect on cardiac output?
stroke volume or heart rate
cardiac output = stoke volume x heart rate
CO = SV x HR
the amount of blood ejected per heart beat is ____ _____
stroke volume
what is the average resting SV and HR
70 ml and 60-80 bpm
changes in HR are affected by reflex controls of the ______ nervous system, ______ nervous system, and ________ activity
central/ autonomic/ baroreceptor
_______ impulses slow the HR and _______ impulses increase the HR
parasympathetic/ sympathetic
how does the sympathetic nervous system increase the HR
by increased level of catecholamines and excess thyroid hormone which produces a catecholamine like effect
_______ specialized nerved cellls located in the aortic arch and in right and left carotid arteries
baroreceptors
during _________ baroreceptors increase their rate of discharge and transmit impulses to the medulla. this initiates parasympathetic activity and inhibits sympathetic activitylowering the BP and HR
hypertension
_______ results in less baroreceptor activity, decreases in paraysmpathetic activity and increased sympathetic activity resulting in vasoconstriction and increased HR and BP
hypotension
what determines stroke volume?
preload afterload contractility
_____ is the degree of stretch of the ventricular cardiac muscle fibers at the end of diastole. the colume of blood returning to the heart increases resulting in stronger contraction and greater stroke volume
preload
what is preload commonly referred to?
left ventricular end diastolic pressure b/c the volume of blood w/in the ventricle at the end of diastole determines preload and directly affects stroke volume
The Frank Starling law (related to preload)
the greater the initial length or stretch of the cardiac muscle cells the greater the degree of shortening that occurs
what factors reduce preload?
diuresis nitrates excessive loss of blood dehydration
how can you control preload?
IV blood transfusion
______ is resistance to ejection of blood from the ventricle, also determines stroke volume
afterload
systemic vascular resistance?
resistance of systemic BP to left ventricular ejection