2.4.2 Enzyme Action

Question 1

Induced fit hypothesis

Answer 1

• Enzyme active site and substrate collide with sufficient speed and correct orientation
• Changes shape slightly as enzyme-substrate complex forms
• Conformational changes
• Ensure ideal binding arrangement between substrate and enzyme is achieved

Question 2

How do enzymes catalyse reactions?

Answer 2

Reduce activation energy by reducing stability of bonds. An alternate energy pathway is provided with a lower activation energy.