24. replication and recombination** Flashcards

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1
Q

how is DNA replicated in bacteria?

A
  • a single chromosome replicated in 42 min
    – started from single origin of replication and proceeding around circle bidirectionally
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2
Q

how is the process initiated?

A
  • occurs at specific nucleotide sequence
    – at ori
    – when various proteins bind to begin replication
  • some proteins that bind to origin of replication are important in making single-stranded regions of DNA accessible for replication
    – chromosomal DNA wrapped around histones/histone-like proteins and is supercoiled
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3
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