24 Neoplastic - Salivary Flashcards

1
Q

What percent of parotid tumors are benign

A

75-80%

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2
Q

What is mc site of salivary gland neoplasm

A

Parotid 73%

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3
Q

Least common site of salivary neoplasm

A

Submandibular 11%

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4
Q

What is m/c site of malig gland neoplasm

A

Minor salivary glands 60%; 40% occur on palate

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5
Q

What is least common site of malig salivary gland neoplasm

A

Parotid 32%

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6
Q

Which salivary gland has best prog for malig tumor

A

parotid

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7
Q

which salivary gland has worst prog for malig tumor

A

SMG

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8
Q

M/c tumor of parotid

A

Pleomorphic adenoma in adult, hemangioma in kid (other sources say BMT in both)

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9
Q

How does metastasizing BMT differ from carcinoma ex-pleomorphic adenoma

A

Histologically benign, lacking malig epithelial components

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10
Q

M/c malig tumor of parotid in adults

A

Mucoep CA

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11
Q

Most imp prog factor for malign salivary gland neoplasms

A

stage

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12
Q

Which 5 salivary gland tumors have worst prog

A
  • High grade mucoep
  • AdenoCA
  • SCCa
  • Undifferentiated CA
  • Carcinoma ex-pleomorphic adenoma
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13
Q

Indications for postop RT after parotid

A
  • High probability of residual microscopic dz
    • margins
  • Advanced stage
  • High grade
  • Deep lobe tumors
  • Recurrent tumors
  • Presence of regional mets
  • Angiolymphatic invasion
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14
Q

What factors are predictors of occult regional dz in parotid CA

A
  • Extracapsular extension
  • Preop facial paralysis
  • Age > 54
  • Perilymphatic invasion
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15
Q

Indications for neck dissection in tx of salivary gland malignancies

A
  • Clinical mets
  • Submandibular tumor
  • SCCa
  • Undifferentiated CA
  • Size > 4 cm
  • High grade mucoep CA
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16
Q

M/c site of distant mets for adenoid cystic CA

A

Lung

17
Q

Incidence of subclinical neck dz w/ adenoid cystic CA of parotid

A

10%

18
Q

M/c salivary gland malig following RT

A

Mucoep

19
Q

M/c malig of SMG and minor salivary glands

A

adenoid cystic

20
Q

Type of tumor comprises 50% of all lacrimal gland neoplasms

A

Adenoid cystic

21
Q

4 types of growth patterns of ACC and which is m/c

A
  • Cribriform (m/c, looks like swiss cheese)
  • Tubular/ductular
  • Trabecular
  • Solid
22
Q

Which type of RT does ACC respond best to

A

Neutron beam

23
Q

What is m/c salivary gland malig to occur bilaterally

A

Acinic cell

24
Q

What are the 2 m/c malig tumors of parotid in children < 12

A

Mucoep is m/c followed by acinic cell

25
Q

Incidence of cervical mets of mucoep CA

A

30-40%

26
Q

Your patient has a mucoepidermoid carcinoma of the parotid gland. Histologic evaluation of the biopsy specimen reveals a scant amount of mucin. There is no clinical evidence of regional metastasis. Do you treat the neck?

A

Yes (this is high grade)

27
Q

What is the 2nd m/c malign tumor of minor salivary glands

A

AdenoCA

28
Q

What are the 4 types of monomorphic adenomas

A

Basal cell
Trabecular
Canalicular
Tubular

29
Q

Which salivary gland tumor is more common in women with a h/o breast CA

A

Mucoep CA

30
Q

What is the tx of choice for met cutaneous SCCa to the parotid

A

Total parotid with preservation of VII (unless invaded by tumor) and postop RT to parotid and IPSI neck

31
Q

What % of malig tumors of parotid p/w facial nerve weakness or paralysis

A

20%

32
Q

Which salivary gland tumor has high propesity for PNI

A

ACC

33
Q

What are the clinical features of salivary duct carcinomas

A

M/c involve the parotid gland and present as an Asx mass; higher incidence in males; distant mets are the m/c cause of death

34
Q

Parapharyngeal tumors arising from deep lobe of parotid will involve which compartment

A

Prestyloid

35
Q

What happens to carotid sheath with deep lobe parotid tumors extending into PPS

A

displaced posteriorly

36
Q

Which compartment of PPS are neurogenic tumors most likely to arise in

A

Poststyloid

37
Q

What is m/c tumor of PPS

A

BMT