2.2 Bone Flashcards
CGCG etiology
unknown (reactive vs benign neoplasm)
CGCG age
< 30 years
CGCG location
anterior Mn
giant cells within background of mesenchyme
CGCG
CGCG Tx
steroids
calcitonin
(or peripheral osteotomy)
CGCG recurrence rate
20%
cherubism due to what mutation
SH3BP2 (AD + de novo)
cherubism is due to ___ bone lesions
osteolytic
bilateral, multilocular, expansile radiolucency
cherubism
giant cells within vascular fibrous tissue
cherubism
fibro-osseous lesions of the jaw (3)
fibrous dysplasia
ossifying fibroma
cemento-osseous dysplasia
fibrous dysplasia due to ___ mutation
GNAS
fibrous dysplasia is MC ___ disease
monostotic
fibrous dysplasia MC location
posterior Mx
polyostotic fibrous dysplasia features
1st decade
female
___ ___ associated with cafe au lait spots
fibrous dysplasia
ground-glass opacification with poorly-defined borders
BL expansion
poorly-defined LD
fibrous dysplasia
MC fibro-osseous lesion
cemento-osseous dysplasia
PA cemento-osseous dysplasia presentation
Mn anterior (multiple sites)
black female adult
PA cemento-osseous dysplasia radiographic presentation
early: lucency
older/intermediate: mixed
end: opacity with lucent rim
focal cemento-osseous dysplasia presentation
Mn posterior (one site)
black female adult
florid cemento-osseous dysplasia presentation
may include all four quadrants
black female adult
cemento-osseous dysplasia Tx
Why?
observe
prone to necrosis (especially sclerotic phase)
ossifying fibroma presentation
posterior Mn
adult
painless swelling (if large)
ossifying fibroma radiographic presentation
mixed or well-defined radiolucency
BL expansion
downward bowing of inferior cortex