2.2 - Biological Molecules Flashcards

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1
Q
A
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2
Q

Draw a water molecule and label the charges on the atoms

A

Delta positive charge on H

Delta negative charge on O

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4
Q

What bonds are formed between the hydrogen and oxygen of different water molecules?

A

Hydrogen bonds

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5
Q

What does it mean for a molecule to be polar?

A

It means the molecule has an unequal spread of electrons so has partial charges within the molecule

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6
Q

How are the electrons shared within a water molecule? Why?

A

Unequally, electrons spend more time around oxygen because:

  • Oxygen is highly electronegative element, more electronegative than hydrogen
  • Therefore the oxygen atom attracts electrons towards it
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7
Q

How is a hydrogen bond drawn?

A

A dotted line

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8
Q

Between which atoms does a Hydrogen bond form?

A

Hydrogen and Oxygen of different water molecules

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9
Q

What is the difference between adhesion and cohesion?

A

Adhesion is when water ‘sticks’ to another surface whereas cohesion is when water is attracted to other water molecules.

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10
Q

What is meant by a high specific heat capacity of water?

A

A lot of energy is require to increase the temperature of water

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11
Q

Why does water have a high specific heat capacity?

A
  • the hydrogen bonds between the molecules must be overcome to increase the temperature of water
  • this requires energy
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12
Q

Why does ice float on liquid water?

A
  • When water freezes a crystal lattice structure is formed so the molecules are held further apart
  • this decreases density
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13
Q

Explain what is meant by the phrase ‘like dissolves like’

A
  • polar substances dissolve other polar substances
  • non-polar substances dissolve non-polar substances
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14
Q

Name 6 physical properties of water

A
  • High specific heat capacity
  • High latent heat of evaporation
  • Ice floats on liquid water
  • Surface tension
  • Can act as a solvent for polar molecules
  • Good transport medium
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15
Q

How does a high latent heat of evaporation of water help organisms to survive?

A

A lot of energy is required to change water from liquid to gas therefore it is very effective in cooling surfaces by evaporation. This helps animals in hot environments (E.g dogs panting)

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16
Q

How does the ability of ice to float on liquid water enable organisms to survive? (3 ways)

A

1-Provides LAND animals a means of sheltering and catching food even in freezing temperatures

2-Floating ice insulates water floating underneath, assisting aquatic animals survival in low temperatures as they do not freeze

3-Ice insulates water so water remains liquid and organisms can still swim and catch prey

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17
Q

How does water as a liquid assist the survival of organisms? (5 ways)

A
  • Water is polar so is a good solvent for polar molecules
  • As good solvent water can transport vital substances around organisms (e.g. glucose in the blood)
  • Can dilute toxic substances within an organism
  • Cohesion gives water surface tension which provides invertebrates with a habitat
  • High specific heat capacity means water provides aquatic organisms with a thermostable habitat, ensuring enzymes work optimally
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18
Q

Suggest how water acting as a solvent for ions (such as nitrates) can contribute to a stable environment for aquatic organisms

A
  • Plants are able to absorb the dissolved nitrates and grow well
  • Plants provide food source for other organisms
  • Plants photosynthesise and produce oxygen which is needed by other organisms for survival
  • Nitrates are used to build amino acids in plants
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19
Q

Define Hydrophilic

A

Readily attracted to water

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20
Q

Define Hydrophobic

A

Repelled by water

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21
Q

Why do hydrogen bonds form between hydrogen and oxygen atoms of different water molecules?

A

Hydrogen has a partial positive charge and Oxygen has a partial negative charge (due to the electronegativity of oxygen) so they attract and form a hydrogen bond.

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22
Q

What is the function of carbohydrates?

A

To provide energy. This can be immediately (e.g. glucose) or as stored energy (e.g. glycogen in animals and starch in plants).

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23
Q

What are the 3 broad groups carbohydrates can be split into?

A

Monosaccharides, disaccharides, and polysaccharides

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24
Q

What is the general formula for monosaccharides?

A

Cn(H2O)n

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25
Q

What properties must a substance have to be classed as a sugar?

A
  • Must dissolve in water
  • Must be crystalline
  • Must be sweet to taste
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26
Q

Are all monosaccharides classed as sugars?

A

Yes

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27
Q

What is the general name for monosaccharides containing:

a) 3 carbons
b) 5 carbons
c) 6 carbons

A

a) triose
b) pentose
c) hexose

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28
Q

Give an example of a 3 carbon sugar

A

G3P

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29
Q

How is sucrose formed?

A

A condensation reaction between alpha glucose and fructose

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30
Q

What hydrolyses sucrose?

A

Sucrase

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31
Q

Give 3 examples of disaccharides

A

Maltose, sucrose, and lactose

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32
Q

What kind of bond forms between sugars in a condensation reaction?

A

A glycosidic bond

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33
Q

How is maltose formed?

A

From a condensation reaction between two alpha glucose molecules

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34
Q

What hydrolyses maltose?

A

Maltase

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35
Q

How do two alpha glucose molecules bond to form maltose?

A

There is a reaction between the hydroxyl group of Carbon 1 of one molecule and Carbon 4 of the other molecule (be careful to specify C1 of one molecule and C4 of another)

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37
Q

Is the bond formed in the condensation reaction of alpha glucose above or below the plane of the ring?

A

Below

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38
Q

Give the two functions of polysaccharides

A

1) Energy storage
2) Structure in the form of cellulose in plant cell walls or chitin in insect wings and fungi walls

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39
Q

In what form is energy stored in:

i) plant cells
ii) animal cells

A

i) Starch
ii) Glycogen

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40
Q

Why are polysaccharides not classed as sugars? (3 reasons)

A
  • They do not taste sweet
  • They are not crystalline
  • They do not dissolve in water
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41
Q

What are the three physical properties of both starch and glycogen that make them excellent storage molecules?

A
  • They are insoluble in water
  • They form very compact molecules
  • They can be easily hydrolysed to release a glucose
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42
Q

(i) How does Starch and glycogen’s insolubility in water make them good storage molecules?
(ii) What would happen if they were soluble in water?

A

(i) They do not dissolve and therefore do not affect the water potential of cells
(ii) They would dissolve and change the water potential of the cell, causing water to move into the cell by osmosis and cause cell damage

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43
Q

Why is the ability to form compact molecules favourable for a storage molecule?

A

A lot of the molecules can fit into a small space, meaning more efficient storage

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44
Q

Why is it beneficial that starch and glucose can be easily hydrolysed?

A

Easy hydrolysis means that both starch and glycogen can provide a readily available source of glucose for respiration and so provide quick release energy.

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45
Q

What reacts to form glycogen?

A

Alpha glucose

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46
Q

What type of bonding occurs in glycogen? Why?

A

1,4 and 1,6 glycosidic bonding

  • This allows for branching so each molecule has many ends where glucose can be added
  • This means glycogen is a more compact molecule
  • This means more terminal glucose molecules that can be simultaneously hydrolysed
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47
Q

What are the two components of starch?

A

Amylose and Amylopectin

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48
Q

i) What happens to the shape of amylose once it has been formed?
ii) What shape does this give it?
iii) What causes this change in shape to occur?

A

i) It coils
ii) Giving a helical shape
iii) Hydrogen bonds form within the coil

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49
Q

i) Which molecules make up amylose?
ii) What kind of bonding links these together?
iii) Therefore what kind of molecules is produced?

A

i) Alpha-glucose
ii) 1,4 glycosidic bonds
iii) Linear

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50
Q

i) What molecules make up amylopectin?
ii) What kind of bonding is present in amylopectin?
iii) Therefore which molecule is amylopectin similar to?

A

i) Alpha-glucose
ii) 1,4 and 1,6 glycosidic bonds
iii) Glycogen

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51
Q

i) How can the presence of starch be tested for?
ii) What is observed if starch is present?
iii) Why does this occur?

A

i) Potassium iodide solution is added
ii) The solution will go from being orange/brown to black/blue
iii) The iodine sits in the coils of the amylose component of starch, this complex appears blue/black

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52
Q

Where is cellulose found?

A

In plant cell walls

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53
Q

What is the monomeric unit of cellulose?

A

Beta glucose

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54
Q

What is the difference between alpha and beta glucose?

A

The OH group on Carbon 1 is above the plane of the ring in beta glucose but below the plane of the ring in alpha glucose

55
Q

i) What bonding is present in cellulose?
ii) What issue arises with this bonding?
iii) Therefore what must happen to allow the bonding to occur?

A

i) 1, 4 glycosidic bonds between beta glucose molecule ii) The hydroxyl groups lie on different planes of the ring iii) Every other beta glucose must be rotated 180 degrees relative to the previous beta glucose

56
Q

What are the monomeric units of sucrose?

A

Alpha glucose and fructose

57
Q

Are all monosaccarides reducing sugars?

A

Yes

58
Q

Are all disaccharides reducing sugars?

A

No, only some are

59
Q

Give an example of a non-reducing sugar

A

Sucrose

60
Q

Give an example of a reducing sugar

A

Maltose or lactose

61
Q

Give an example of a 5 carbon sugar

A

Ribose or deoxyribose

62
Q

Give an example of a 6 carbon sugar

A

Glucose or fructose or galactose

63
Q

What type of reaction is the breakdown of maltose by maltase?

A

Hydrolysis

64
Q

What is produced by the hydrolysis of maltose?

A

Two alpha glucose molecules

65
Q

What is a reducing sugar?

A

Sugars that donate electrons resulting in the reduction of another molecule

66
Q

What are the 3 types of lipids?

A
  • Triglycerides
  • Phospholipids
  • Sterols
67
Q

What are the 5 functions of triglycerides?

A
  • Major source of energy
  • Source of metabolic water
  • Makes up adipose tissue
  • provides thermal insulation under skin of animals
  • Provides protection around internal organs
68
Q

How do triglycerides compare to carbohydrates in terms of energy?

A

-Per g triglycerides release more energy

69
Q

Being a source of metabolic water makes them useful for organisms in what kind of environment?

A

Desert

70
Q

Give an example of an animal that uses triglycerides as thermal insulation

A

Killer whale in the form of blubber

71
Q

When are triglycerides stored as adipose tissue?

A

When energy input is greater than energy output

72
Q

Why is cholesterol transported as a lipoprotein?

A

They allow lipids and cholesterol to dissolve in the blood

73
Q

What are the functions of sterols (2 functions)?

A

-Cholesterol used in cell membranes to give stability and regulate fluidity -Used to make steroid hormones

74
Q

Give 2 examples of steroid hormones

A

Testosterone and oestrogen

75
Q

Where is cholesterol manufactured?

A

The liver and intestines

76
Q

What is the function of HDL?

A

-used to make cell membranes and organelle membranes -decreases membrane fluidity

77
Q

Which is ‘good’ cholesterol; HDL or LDL?

A

HDL

78
Q

What does too much LDL lead to?

A

-atherosclerosis (deposits in artery walls) -gall stones

79
Q

How are triglycerides formed?

A

A condensation reaction between a glycerol molecule and 3 fatty acids

80
Q

What kind of bonds are formed when a triglyceride is formed?

A

Ester bonds

81
Q

Which part of a glycerol molecule takes part in the condensation reaction to form a triglyceride?

A

The hydroxyl groups

82
Q

What is the structure of a glycerol molecule?

A
83
Q

What are the 3 types of lipids?

A
  • Triglycerides
  • Phospholipids
  • Sterols
84
Q

How many molecules of water are formed from the condensation reaction to form a triglyceride?

A

3

85
Q

What does a hydrolysis reaction of a triglyceride produce?

A

A glycerol molecule and 3 fatty acids

86
Q

i) How are phospholipids formed? ii) What kind of bonds are formed?

A

i) A condensation reaction between a glycerol molecule, 2 fatty acids, and a phosphate group ii) Ester bonds

87
Q

What property does the head of a phospholipid have?

A

It is hydrophillic and polar

88
Q

What property does the tail for a phosphlipid have?

A

It is hydrophobic and non-polar

89
Q

Draw a simplified version of a phospholipid

A
90
Q

Draw a phospholipid bilayer

A
91
Q

Explain the differences between phospholipids and triglycerides

A

-Triglycerides contain 3 fatty acids but phospholipids only contain two and a phosphate group - Triglycerides contain 3 ester bonds but phospholipids only contain 2 - Phospholipids have a hydrophilic head

92
Q

What are the 5 functions of triglycerides?

A
  • Major source of energy
  • Source of metabolic water
  • Makes up adipose tissue
  • provides thermal insulation under skin of animals
  • Provides protection around internal organs
93
Q

How do triglycerides compare to carbohydrates in terms of energy?

A

-Per g triglycerides release more energy

94
Q

Explain why membranes exist as bilayers

A

-Both the inside and outside of cells are aqueous -therefore a single layer would repel on one side -Bilayers mean that hydrophilic heads can face into the tissue fluid and cytoplasm -with the hydrophobic tails facing away from the aqueous environments

95
Q

How does cholesterol sit in phospholipid bilayers?

A

With the hydroxyl group in contact with the Phosphate head

96
Q

What are sterols made up of?

A

Large alcohol molecules

97
Q

As cholesterol increases membrane fluidity ____

A

Decreases

98
Q

A decrease in cholesterol ____ fluidity

A

Increases

99
Q

How can you test for the presence of lipids?

A

Add ethanol first and then the resulting mixture add to water and shake

100
Q

State two roles of cholesterol in living organisms

A

1) Increases stability of phospholipds in cell membrane 2) Waterproofing to skin

101
Q

Name two molecules that combine with cholesterol to form LDLs

A

1) Saturated fatty acids 2) Triglycerides/lipids

102
Q

Being a source of metabolic water makes them useful for organisms in what kind of environment?

A

Desert

103
Q

Give an example of an animal that uses triglycerides as thermal insulation

A

Killer whale in the form of blubber

104
Q

When are triglycerides stored as adipose tissue?

A

When energy input is greater than energy output

105
Q

What is the structure of a glycerol molecule?

A
106
Q

Why is cholesterol transported as a lipoprotein?

A

They allow lipids and cholesterol to dissolve in the blood

107
Q

What are the functions of sterols (2 functions)?

A

-Cholesterol used in cell membranes to give stability and regulate fluidity -Used to make steroid hormones

108
Q

Give 2 examples of steroid hormones

A

Testosterone and oestrogen

109
Q

Where is cholesterol manufactured?

A

The liver and intestines

110
Q

What is the function of HDL?

A

-used to make cell membranes and organelle membranes -decreases membrane fluidity

111
Q

Draw a phospholipid bilayer

A
112
Q

Draw a simplified version of a phospholipid

A
113
Q

Which is ‘good’ cholesterol; HDL or LDL?

A

HDL

114
Q

What does too much LDL lead to?

A

-atherosclerosis (deposits in artery walls) -gall stones

115
Q

How are triglycerides formed?

A

A condensation reaction between a glycerol molecule and 3 fatty acids

116
Q

What kind of bonds are formed when a triglyceride is formed?

A

Ester bonds

117
Q

Which part of a glycerol molecule takes part in the condensation reaction to form a triglyceride?

A

The hydroxyl groups

119
Q

How many molecules of water are formed from the condensation reaction to form a triglyceride?

A

3

120
Q

What does a hydrolysis reaction of a triglyceride produce?

A

A glycerol molecule and 3 fatty acids

121
Q

i) How are phospholipids formed? ii) What kind of bonds are formed?

A

i) A condensation reaction between a glycerol molecule, 2 fatty acids, and a phosphate group ii) Ester bonds

122
Q

What property does the head of a phospholipid have?

A

It is hydrophillic and polar

123
Q

Explain the differences between phospholipids and triglycerides

A

-Triglycerides contain 3 fatty acids but phospholipids only contain two and a phosphate group - Triglycerides contain 3 ester bonds but phospholipids only contain 2 - Phospholipids have a hydrophilic head

124
Q

What property does the tail for a phosphlipid have?

A

It is hydrophobic and non-polar

125
Q

Name two molecules that combine with cholesterol to form LDLs

A

1) Saturated fatty acids 2) Triglycerides/lipids

126
Q

State two roles of cholesterol in living organisms

A

1) Increases stability of phospholipds in cell membrane 2) Waterproofing to skin

127
Q

How can you test for the presence of lipids?

A

Add ethanol first and then the resulting mixture add to water and shake

128
Q

A decrease in cholesterol ____ fluidity

A

Increases

129
Q

As cholesterol increases membrane fluidity ____

A

Decreases

130
Q

What are sterols made up of?

A

Large alcohol molecules

131
Q

How does cholesterol sit in phospholipid bilayers?

A

With the hydroxyl group in contact with the Phosphate head

132
Q

Explain why membranes exist as bilayers

A

-Both the inside and outside of cells are aqueous -therefore a single layer would repel on one side -Bilayers mean that hydrophilic heads can face into the tissue fluid and cytoplasm -with the hydrophobic tails facing away from the aqueous environments