2154 Respiratory Flashcards

1
Q

Codeine & dextromethorphan supply limit + CI

A

Limit to 240 mL within 4 days
CI: MAOi

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2
Q

cough drugs safe to use in pregnancy (2)

A

Dextromethorphan & Guaifenesin (lowest dose & shortest duration)

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3
Q

Oral Decongestant caution (4)

A
  1. uncontrolled BP
  2. Glaucoma
  3. BPH
  4. Hyperthyroidism
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4
Q

TOP Decongestant ADR + pregnancy alternative

A

rebound congestion = do not use > 5 days (pregnancy use saline)

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5
Q

Antihistamine caution (3)

A
  1. Avoid in elderly with BPH / glaucoma
  2. Avoid alcohol, opioids, antidepressant
  3. Pregnancy use chlorpheniramine
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6
Q

intranasal corticosteroids sprays caution (2)

A

worsen
1. Glaucoma
2. Cataract

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7
Q

Leukotriene antagonist (Montelukast) ADR (2)

A
  1. Neuropsychiatric SE
  2. Behavioural / mood changes
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8
Q

SABA (salbutamol) ADR

A
  1. Tremor, muscle cramp
  2. Tachycardia / palpitation
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9
Q

ICS (steroids) ADR (2)

A
  1. Oral Candidiasis –> rinse & spit out water after
  2. throat irritation, hoarseness, cough
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10
Q

LAMA (Umeclidinium) ADR

A

Anticholinergic (dry mouth, tachycardia, urinary retention)

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11
Q

COPD Groups & treatment (3)

A
  1. Group E: > 2 exacerbation or hospitalisation = LABA + LAMA +/- ICS
  2. Group B: mMRC > 2 = LABA + LAMA
  3. Group A: mMRC 0-1 = bronchodilator
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12
Q

mMRC score for COPD (5)

A

0 = least Sx, breathless when exercise
1 = SOB walking up hill
2 = walks slower, stop for breath when walking normally
3 = stops for breath 100m
4 = too breathless to leave house

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13
Q

Indication for ICS in COPD (3)

A
  1. Hx of hospitalisation / asthma
  2. COPD exacerbations > 2 / year
  3. Blood eosinophils > 300
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14
Q

Indications for Abx in COPD exacerbation (2)

A
  1. worsening SOB
  2. increase sputum purulence & volume
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15
Q

Criteria to start NRT (4)

A
  1. Smoke within 1h of waking
  2. > 10 cig /day
  3. Hx of craving / withdrawal in past quit attempts
  4. Nicotine dependence (>3 in score)
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16
Q

Cig per day (CPD) to NRT patch dose

A

< 10 CPD= 7 mg
10-20 CPD = 14 / 21 mg
21-30 CPD = 28 mg
31-40 CPD = 35 mg
> 40 CPD = 42 mg

17
Q

Bupropion SR avoid (3)

A
  1. Psychiatric patients (seizure, schizo, bipolar)
  2. Pregnancy & breastfeeding
  3. Under 18
18
Q

Varenicline avoid (3)

A
  1. Pregnancy
  2. ESCKD
  3. Sx of agitation, depression, suicidal thoughts, behavioural changes
19
Q

Cisplastin & Carboplatin ADR (3)

A
  1. CINV
  2. Ototoxicity & nephrotoxicity
  3. Peripheral neuropathy
20
Q

administration supp with cisplatin (3)

A
  1. Vigorous hydration
  2. IV NaCl pre & concurrent
  3. KCl & MgSO4 supp (electrolyte)
21
Q

Pemetrexed avoid (2) + supp (3)

A

avoid NSAIDs & CrCl < 45
Supp: Folic acid + vit B12 + dexamethasone

22
Q

Tyrosine Kinase inhibitor (Osimertinib) instruction & DDI

A

take on empty stomach
DDI with CYP3A4 (PPI, H2RA, statin, warfarin)

23
Q

Red flag questions for respiratory (4)

A
  1. Unintentional weight loss, night sweat (TB)
  2. Dyspnoea / SOB
  3. Hemoptysis (vomit blood)
  4. Long lasting fever > 7d