21. Mechanism of disease Flashcards
Food insecurity - undernutrition
Lack of/not enough food = lowered immunity = increase susceptibility to communicable diseases e.g. TB, measles, cholera, influenza
Food insecurity - malnutrition
Imbalance of nutrient intake…
- e.g. Vitamin C deficiency = lowered immunity = increased susceptibility to communicable diseases e.g. cholera OR
- e.g. low iron intake = iron deficiency anaemia = low levels of red blood cells (haemoglobin) in the blood which is responsible for carrying oxygen to the cells = fatigue OR
- e.g. calcium deficiency = osteoporosis = brittle bones = increase risk of fracture (injury)
Male - injuries
Higher levels of hormone testosterone = increased risk taking behaviours e.g. driving while intoxicated = injuries e.g. head and/or spinal injury
Post-menopausal female - CVD and osteoporosis
Lower levels of hormone oestrogen (compared to pre-menopausal levels) = protective factor for women against CVD and osteoporosis up until menopause therefore increased risk after menopause
Smoking - CVD
Inhalation of dangerous chemicals from tobacco smoke = increases the rate of atherosclerosis = sticky plaque build up on blood vessel walls causing hardening and potential blockages resulting in…
- heart attack (coronary heart disease - reduced oxygen flow to heart) AND/OR
- stroke (reduced oxygen flow to the brain)
Smoking - lung cancer
Inhalation of dangerous chemicals in tobacco smoke into the lungs = increased risk of abnormal cell growth in the lungs
Smoking - asthma
Inhalation of dangerous chemicals in tobacco smoke into the lungs = narrowing and inflammation of airways reducing oxygen flow
Smoking - COPD
Inhalation of dangerous chemicals in tobacco smoke into the lungs = progressive, long term lung damage = obstruction of oxygen intake = making breathing difficult = e.g. emphysema, bronchitis
Alcohol - obesity
Alcohol is energy dense = increase risk of positive energy balance = weight gain/excess adipose tissue storage = high BMI/obesity
Alcohol - CVD
Alcohol is energy dense = increase risk of positive energy balance = weight gain/excess adipose tissue storage = high BMI/obesity = strain on the heart = increase risk heart attack (coronary heart disease)
Alcohol - Type 2 diabetes
Alcohol is energy dense = increase risk of positive energy balance = weight gain/excess adipose tissue storage = high BMI/obesity = strain on pancreas = inability to release insulin effectively to regulate blood glucose levels
Alcohol - liver diseases
Alcohol is filtered by the liver = excess consumption places strain on the liver to perform this function = liver damage/cirrhosis/disease/failure AND/OR abnormal cell growth in the liver = liver cancer
Alcohol - mental health disturbances e.g. depression
Alcohol is a depressant drug = slowing down messages within central nervous system and altering behaviour = which may result in…
- regrettable actions e.g. drink driving fatality
- strain on relationships e.g. fight with friend when intoxicated AND/OR
- addiction e.g. causing financial stress
= mental health disturbances e.g. depression
Alcohol - injuries
Alcohol is a depressant drug = slowing down messages within central nervous system and slowing down reaction time, also can increase risk taking behaviours e.g. driving while intoxicated, swimming while intoxicated, jumping off balcony, etc. = injuries such as broken leg, head and/or spinal injury, etc.
High BMI - CVD
Excess adipose tissue = strain on the heart = increase risk of heart attack/ischaemic heart disease/coronary heart disease (reduced oxygen flow to the heart)
High BMI - cancer
Excess adipose tissue = increase risk of a range of cancers (abnormal and uncontrollable cell growth) e.g. stomach cancer, kidney cancer
High BMI - osteoarthritis
Excess adipose tissue = increase strain on joints e.g. knee = increase risk of osteoarthritis (wearing down of cartilage between the joints causing inflammation, pain, stiffness)