2022 Canadian Urological Association recommendations on prostate cancer screening and early diagnosis Flashcards
What was the sample size of the PLCO trial in the 2017 update?
76,683
What is the age range for participants in the ERSPC trial (2014 update)?
55-69
How many European countries participated in the ERSPC trial?
8 European countries
How frequently was PSA screening done in the Goteborg trial (2014 update)?
Every 2 years
In the PLCO trial, how was a positive test defined?
PSA >4 ng/ml or an abnormal DRE
In the ERSPC trial, how was a positive test defined?
PSA >3.4 ng/ml
What was the rate ratio for CSS in the Goteborg trial (2014 update)?
0.58 (0.46-0.72)
Which trial reported a 42% relative risk reduction in favor of screening?
Goteborg (2014 update)
What does NNS stand for?
Number needed to screen
How many prostate cancer deaths were reported in the screened group of the ERSPC trial?
355
In the Goteborg trial, what was the NND?
1:13
Which trial had a median follow-up of 18 years?
Goteborg (2014 update)
What does CSS stand for?
Prostate cancer-specific survival
Which trial conducted the PSA screening annually for 6 years and had an annual DRE for 4 years?
PLCO (2017 update)
How many participants were in the ERSPC trial (2014 update)?
162,243
Which trial was conducted across 10 US centers?
PLCO (2017 update)
Where was the Goteborg trial (2014 update) conducted?
Goteborg, Sweden
In the Goteborg trial, how was a positive test defined from 1999-2004?
PSA >2.9 ng/ml
In the Goteborg trial, how was a positive test defined from 2005 onwards?
PSA >2.5 ng/ml
How many prostate cancer deaths were reported in the control group of the Goteborg trial?
122
What was the rate ratio for CSS in the ERSPC trial (2014 update)?
0.79 (0.69-0.91)
How many prostate cancer deaths were reported in the control group of the PLCO trial?
244
What was the NND for the ERSPC trial?
1:27
What is the age range for participants in the Goteborg trial (2014 update)?
50-64