2021 AS Paper 1 Flashcards

1
Q

Bond between complementary base pairs

A

hydrogen bonds

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2
Q

Bond between adjacent nucleotides in a DNA strand

A

phosphodiester bonds

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3
Q

2 differences between the structure of tRNA and mRNA

A
  • tRNA has an anticodon, mRNA has a codon
  • tRNA has an amino acid binding site, mRNA does not
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4
Q

Describe and explain a difference in the structure of mRNA and pre-mRNA

A

pre-mRNA contains more nucleotides as it contains both exons and introns, mRNA only has exons since its introns are spliced

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5
Q

Describe how HIV is replicated

A
  • attachment protein binds to receptors on the t helper cell
  • RNA enters the cell
  • reverse transcriptase converts the RNA into DNA
  • this releases enzymes
  • virus particles are assembled then released
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6
Q

Explain why it isn’t possible to determine the identity of the structure using an optical microscope

A

optical microscopes have long wavelengths so they have a low resolution

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7
Q

Describe the role of one named organelle in digesting these bacteria

A

lysosomes fuse with the vesicle and release hydrolytic enzymes, allowing the bacteria to be digested

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8
Q

Suggest an explanation for the position of mitochondria in large U. marinum cells using knowledge of SA to volume ratio

A
  • in large cells, there’s a small SA to volume ratio so there’s a larger diffusion distance for oxygen to reach respiring cells
  • mitochondria being close to the cell membrane reduces diffusion distance
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9
Q

Describe and explain the arrangement of genetic material in the figure

A

the chromosomes are becoming visible as they’re condensing to get ready for replication

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10
Q

Name the fixed position occupied by a gene on a DNA molecule

A

locus/loci

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11
Q

Describe how a gene is a code for the production of a polypeptide

A
  • a gene is made up of a sequence of bases
  • three of these bases make up a triplet code
  • this determines the sequence of amino acids
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12
Q

Describe how the structure of glycogen is related to its function

A
  • contains alpha glucose which is easily hydrolysed
  • branched molecule so is compact
  • insoluble so doesn’t affect water potential
  • branched so more ends for faster hydrolysis
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13
Q

Give the pathway a red blood cell takes when travelling in the human circulatory system from a kidney to the lungs

A
  • goes through the renal vein
  • goes through the vena cava into the right atrium then into the right ventricle
  • goes from the right ventricle through the pulmonary artery to the lungs to become oxygenated
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14
Q

Identify the type of blood vessel in the figure (has large lumen)

A

vein as it has a large lumen

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15
Q

Explain how water from tissue fluid is returned to the circulatory system

A
  • plasma proteins remain
  • this reduces the water potential
  • water exits the capillary via osmosis and moves into the blood
  • it returns to the blood by the lymphatic system
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16
Q

Suggest and explain an advantage of carrying out this investigation at 30 degrees rather than 20

A

higher temperature means more kinetic energy, allowing for faster osmosis

17
Q

Identify two organelles in kidney cells that enable the production of EPO

A
  • golgi apparatus
  • ribosomes
18
Q

Explain the biological advantage to athletes of injecting synthetic EPO

A

more oxygen transport so more aerobic respiration at a quicker rate

19
Q

Describe how mice injected with human EPO produce anti-human EPO antibody

A
  • antigens from the human EPO get displayed on the surface of phagocytes
  • this causes t helper cells to stimulate B cells to divide rapidly by mitosis
  • plasma cells produce antibodies which are specific to human EPO
20
Q

Role of anti-human EPO antibody

A

binds to EPO antigen

21
Q

Role of anti-mouse antibody with enzyme attached

A
  • binds to human antibody
  • enzyme induces a colour change
22
Q

Why do people object to the use of monoclonal antibodies

A

unethical as they’re taken from healthy cells