2018 - MCQ Flashcards
Teen girl presents to your office with recurrent episodes of syncope on extreme exertion. She is diagnosed with long QT syndrome. What
is the next best step in management?
a. Calcium channel blocker without high intensity exercise restriction
b. Calcium channel blocker with high intensity exercise restriction
c. Beta-blocker without high intensity exercise restriction
d. Beta-blocker with high intensity exercise restriction
Beta-blocker with high intensity exercise restriction
Adolescent male, who is 97th percentile for height presents with 2/6 systolic murmur at the left lower sternal border that is worse
when he stands up. Two uncles had “MI”s in their 30s. What is your next investigation?
a. Echocardiogram
b. ECG
c. EEG
d. Holter
ECG vs ECHO
Marfans
Child in grade 1 with history of repaired TAPVR. He has been diagnosed with ADHD. After taking a thorough history and physical exam, you next step is: a. ECG b. Echocardiogram c. Start a stimulant medication with no further investigation d. Stimulants are contraindicated ---- a. Start stimulants b. ECG c. Refer to psychiatry d. Continue to monitor
Start a stimulant medication with no further investigation
An adolescent presents with syncope on exercise. On examination you note a parasternal heave and listen to a mid-systolic III/VI murmur radiating to the neck on the 2nd Lt intercostal space. What is the most likely cause:
a. AS
b. MR
c. PS
Aortic stenosis
3-month old with a few days of decreased feeds, vomiting and tachypnea. Presents to ED unresponsive. Cap refill 3 seconds, pulses palpable. Liver edge 5cm. Resp rate 70, Heart rate 230 BPM. Otherwise normal exam. Diagnosis?
a. CHF secondary to myocarditis
b. Inborn error of metabolism
c. SVT
d. sepsis
SVT
8 yo male with CF, 6 weeks cough, congestion, NO fever. +weight loss (no mention of sputum) with decrease in FEV1. Most likely bug?
a. Burkholderia Cepacia
b. Aspergillus
c. Pseudomonas
d. Stenotrophomonas
pseudomonas
16 year old has visited the ED multiple times with acute cough and wheeze. Never responds to bronchodilators. Otherwise healthy and well-adjusted. Which investigation will give you the most likely diagnosis?
a. PFTs
b. CXR
c. Rhinolaryngoscopy
Rhinolaryngoscopy
A teenage boy who is well adjusted presents with recurrent episodes of cough and wheeze that do not respond to a bronchodilator. How will you make the diagnosis? a. Flexible nasolaryngoscopy b. CT chest c. Chest X-ray d. PFTs
Flexible nasolaryngoscopy
A 12 year old with asthma, is on a low dose inhaled corticosteroid. They were previously well controlled, but now use their SABA 4-5 times per week. Other than checking adherence, and technique how do you adjust the treatment?
a. Change to a medium dose ICS
b. Switch to alternate ICS
c. Add a LABA in addition to low dose ICS
d. Add Montelukast
Add a LABA in addition to low dose ICS
What oxygen saturation reading would prompt administration of supplemental oxygen for a one month old with RSV bronchiolitis?
a. 88%
b. 90%
c. 94%
d. 96%
90%
What is the mechanism of risperidone increasing prolactin?
a. Risperidone increases lactotrophs
b. Risperidone blocks dopamine receptors, which usually inhibits prolactin secretion
c. TRH
Risperidone blocks dopamine receptors, which usually inhibits prolactin secretion
Hyponatremia (sodium 116) in a 1-2 month old. Mom has been feeding glucose water. No seizures. Hypotensive (70/46ish) with tachycardia. What do you do?
a. NS maintenance
b. ½ NS maintenance
c. Bolus NS 20mL/kg
Bolus NS 20mL/kg
A newborn baby has bony defects in the sacrum, lumbar vertebrae and also thoracic vertebrae. What is the most common cause?
a. Infant of diabetic mother
b. Trisomy 13
c. Holoprosencephaly
d. FAS
IDM
Baby with jaundice at 4 days of life. Now 1 week old. Total bili 380, conjugated 150-190) and presenting with poor feeding, one episode of vomiting, and temperature of 35. No vital signs mentioned. What is most likely diagnosis?
a. Biliary atresia
b. Galactosemia
c. Neonatal hepatitis
d. Sepsis
e. Alpha 1 antitrypsin (not option on another exam)
sepsis
3 day old infant born at 3000g, now at 2693g, exclusively breast fed, primigravida mother. Mother is feeding 9 times in 24 hours, and baby has 7 wet diapers in the past 24 hours. Physical exam is normal. What do you do?
a. Supplement with 15-30ml formula after each feed
b. Do bloodwork including bili, creatinine and electrolytes
c. Follow closely and weigh baby again in 24 hours, continue breastfeeding.
d. Start mom on motilium/domperidone to increase milk production
Follow closely and weigh baby again in 24 hours, continue breastfeeding.
A mother has HbsAg+. What is the correct management of her newborn?
a. HBIG and vaccine within 12 hours
b. Vaccine within 12h and Ig within 7 days
c. Vaccine now and Ig within 1 month
d. HB vaccine now and do serology in one month
HBIG and vaccine within 12 hours
A 7 day old baby comes to the ED with a history of bloody stool. He is pale and tachycardic with a low hemoglobin. He was born at home, and had an uneventful course. What is the diagnosis?
a. Hemorrhagic disease of the newborn
b. Meckels diverticulum
c. Anal fissure
d. CMPA
Hemorrhagic disease of the newborn
What is the most common long term complication of necrotizing enterocolitis?
a. Intestinal stricture
b. Malabsorption
c. GERD
Intestinal stricture
Cyanotic newborn whose CXR shows large heart and decreased pulmonary vascular markings (oligemic lung fields). What is the MOST common cause (what is the diagnosis)?
a. TOF
b. Truncus arteriosus
c. TGA
d. TAPVR
TOF
Neonate with platelets of 12, otherwise normal CBC, has petechiae. After transfusion platelets are still low. Moms platelets are normal. How do you manage?
A. Transfuse PLA-1 negative platelets.
B. Give IVIG
C. Pooled donor platelets
Transfuse PLA-1 negative platelets
An exclusively breastfed baby comes to your office at five days of life with a total bill of 240, unconjugated. Term. Well. What do you do for management? (No bili chart provided)
A. Admit the child for phototherapy
B. Reassure and continue regular care
Reassure and continue regular care
What is a cause of a false negative sweat chloride? A. Hypothyroidism B. Edema C. Eczema D. Hypogammaglobulinemia
??
Edema and Hypogammaglobulinemia
APGAR scores for a baby. 1 minute: HR 80, grimace with suction, blue, limp, irregular resps. 5 minute: still hypotonic, HR 140, no response to suction, acrocyanosis, irregular resps.
a. 4,4
b. 3,4
c. 3,5
3,5
1,1,0,0,1 and 1,2,0,1,1
Baby with newborn screen positive for PKU, otherwise currently well, no family history. What do you do next?
a. Repeat phenylalanine level
b. Restrict phenylalanine in diet
c. Test for BH4 deficiency
Repeat phenylalanine level versus Restrict phenylalanine in diet
Term newborn baby in the nursery is found to be jittery, tachypneic with nasal flaring, with myoclonus. Normal glucose. Based on the most likely diagnosis, what is your next management?
a. Morphine
b. Benzodiazepine
c. Phenobarbital
d. Ampicillin and Gentamicin
morphine
Why do we irradiate blood given to premature infants.
a. Decrease CMV
b. Decrease GVHD
c. Sterilize RBC
d. Decrease hemolytic reactions
Decrease GVHD
Why do we irradiate blood given to premature infants.
a. Decrease CMV
b. Decrease GVHD
c. Sterilize RBC
d. Decrease hemolytic reactions
Decrease GVHD
Adolescent girl with multiple episodes of fainting after prolonged standing. She has preceding symptoms of light headedness, and vision contraction then going black. On one occasion, her father caught her and kept her in a seated position. She then had a short period of generalized tonic clonic convulsions and loss of bladder control. What is your next investigation?
a. MRI
b. EEG
c. Orthostatic vasovagal syncope
d. Holter monitor
?? Orthostatic vitals?
loss of bladder control may indicate seizure however?
EEG?
A 7-year-old male has idiopathic generalized tonic clonic epilepsy. He is on valproate. He is doing well and has been seizure free for 9 months. The family doctor did a valproate level as a part of his health supervision and it was 290 (normal 350-700). What do you do?
a. No change to valproate dose
b. Increase the valproate to therapeutic range
c. Discontinue the valproate since he doesn’t need it
No change to valproate dose (TB)
A child who is typically on clobazam for seizures has a GTC seizure at home witnessed by the father. His father gave him a dose of IN midazolam that stopped the seizure in 2 minutes. 10 minutes after arriving to the ED, he has another GTC. What will be your INITIAL treatment?
a. IV phenytoin
b. IV fosphenytoin
c. Intranasal midazolam
d. IV midazolam
IV midazolam??
Do they have an IV?
Intranasal midaz also seems ok?
A child develops bilateral ascending paralysis after a GI infection (diarrhea) with stool cultures positive for campylobacter. Nerve
conduction studies show neuropathy. What is the management?
a. Pulsed Steroids
b. IVIG
c. Antibiotics
d. NSAIDs
IVIG
Guillain Barre Syndrome
A 3 year old girl presents to your clinic, with concerns that she has had a recent increase in falling. She was noted by her mother to walk at 11 months of age. On examination you note bilateral increased tone in her lower extremities. What is your diagnosis?
a. X-linked Adrenoleukodystrophy
b. Metachromatic leukodystrophy
c. Spastic diplegic cerebral palsy
d. Myotonic dystrophy
?
Spastic diplegic cerebral palsy (TB)
A child presents with polyuria, and polydipsia. Her serum sodium is 150, and her urine is very dilute (low specific gravity). Administration of vasopressin results in the rapid decrease in serum osmolality, and increase in urine osmolarity. MRI brain demonstrates thickening of the pituitary stalk. What is the diagnosis?
a. Histiocytosis
b. Craniopharyngioma
c. Prolactinoma
d. Hypothalamic hamartoma
Histiocytosis - b/c of thickening of the pituitary stalk
What is the most specific indicator of seizure activity in a neonate?
a. Irregular respirations
b. Tachycardia
c. Eye movements
Eye movements
2-year-old child presents with proximal muscle weakness and decreased DTRs in the legs what is the diagnosis?
a. Congenital myopathy
b. Neuromuscular junction
c. Peripheral neuropathy - is possible, but would likely be more distal
d. Spinal cord injury
Congenital myopathy (TB)
Term newborn baby in the nursery is found to be jittery, tachypneic with nasal flaring, with myoclonus. Normal glucose. Based on the most likely diagnosis, what is your next management?
a. Morphine
b. Benzodiazepine
c. Phenobarbital
d. Ampicillin and Gentamicin
morphine
5 month old with vomiting for 6 hours intermittently, has had 3 or 4 episodes of flexion and extension of arms and legs, drowsy after, abdomen is distended, which test would reveal diagnosis?
a. EEG
b. CT abdomen
c. Abdominal ultrasound
d. Abdominal XR
Abdo U/S for intussusception
Could also be infantile spasms? - then EEG
3 year old boy with nephrotic syndrome, started on steroids. Presents with abdominal pain and distended abdomen with dullness over the flanks bilaterally with diffuse rebound tenderness. Which investigation is most likely to confirm your diagnosis?
a. Abdominal X-ray
b. Exploratory laparotomy
c. Barium swallow
d. Paracentesis
- ————————
a. CT abdomen
b. Paracentesis and culture
c. Abdominal U/S
d. Surgical exploration? Or ?laparotomy
Paracentesis
3 week old hospitalized male, who has a history of antenatally diagnosed hydronephrosis. He has had a post natal ultrasound that showed moderate to severe unilateral hydronephrosis. Normal renal function. How do you manage the infant?
a. Consult urology prior to discharge
b. Order an outpatient VCUG
c. DMSA
d. Reassure
Consult urology prior to discharge
A 15 year old boy presents with 24-hour history of acute dysuria, pyuria. He has a tender scrotum with swelling. Urinalysis shows
WBC. What is the best course of management?
a. Antimicrobials for him
b. Antimicrobials for him and his sexual partner
c. Consultation to urology for surgical detorsion
d. Rest, analgesia and supportive care
Antimicrobials for him and his sexual partner
A 4-month-old infant female presents with failure to thrive and the following bloodwork:
Gas: pH 7.24, CO2 30, HCO3 16. BW: Na 138, Cl 111, K 5, PO4 2.1, glucose 4. What is the underlying disease?
a. Renal tubular acidosis
b. Cystic fibrosis
c. Fanconi syndrome
d. Mitochondrial disorder
RTA
Child with nephrotic syndrome. What is the most likely consequence associated with this disorder?
a. DVT
b. Encephalopathy
c. Acute renal failure
d. Heart failure
DVT
Child presents with brown urine. UA with hematuria and proteinuria. Hypertensive to sBP 160. C3 and C4 are both normal. What is likely diagnosis?
a. IgA nephropathy
b. MPGN
c. PSGN
d. SLE
IgA nephropathy
- only one with normal C3
12 year old girl with 3 weeks of fever, malaise and polyarthralgias (migratory). No arthritis. On exam today appears pale, joint
exam is normal. Bloodwork shows: ESR 75, creatinine 59, WBC 3, normal platelets. Lymphopenia. Urine shows trace blood
and protein. What is the most likely diagnosis?
a. SLE
b. Systemic JIA
c. Rheumatic fever
d. Post-streptococcal GN
e. Septic arthritis
SLE
A child with Kawasaki disease received IVIG. 24-hours later, she develops gross hematuria, with 3+blood and protein present on
urine dipstick. Her lab work demonstrates elevated unconjugated bilirubin, LDH, and transaminases. What is the cause of this reaction?
a. Hemolytic IVIG reaction
b. Renal vein thrombosis
c. Anaphylaxis
d. High-dose ASA causing bleeding
Hemolytic IVIG reaction
A child is diagnosed with systemic JIA, and now presents with evidence of macrophage activation syndrome (cannot remember the
labs) . What of the following will be reduced?
a. fibrinogen
b. LDH
c. triglycerides
d. Ferritin
fibrinogen
A school aged girl who plays soccer comes to your office with concerns of persistent heel pain. She has pain in running and jumping while playing soccer but not in swimming. When you squeeze her Achilles’ tendon, it hurts. What is the diagnosis? A. Calcaneal apophysitis B. Achilles tendonitis C. Plantar fasciitis D. Calcaneal stress fracture
??
Calcanea apophysitis versus Achilles tendonitis
12-year-old kid comes in with rib pain and a few weeks of fever. White count is normal. Chest x ray shows mottled appearance of ninth rib with periosteal reaction and new bone formation. Most likely diagnosis?
a. Osteosarcoma
b. Ewing sarcoma
c. Osteoid osteoma
d. Osteomyelitis
Ewing’s sarcoma
3 year old with a fever of 39.1˚C and severe ear pain for 2 days. On exam the tympanic membrane is bulging and erythematous. What is the best management plan?
a. Amoxicillin (75-90 mg/kg) BID for 5 days
b. Observe and re-examine after 24-48 hrs.
c. Offer a Rx for amoxicillin but tell the family to fill it if symptoms persist for another 24hr
d. Amoxicillin (75-90 mg/kg) BID for 10 day.
Amoxicillin (75-90 mg/kg) BID for 5 days
> 2yo
A child is admitted with S. pneumoniae bacteremia and is started on Ampicillin. Shortly after receiving antibiotics, they are noted to have decreased LOC and urticaria. Tachycardic and Hypotension are noted. What is the best next step?
a. Benadryl IV.
b. 20ml/kg NS bolus.
c. Epinephrine 0.01mg/kg IV
d. Oral cetirizine
- ——
a. IV diphenhydramine
b. Restart ceftriaxone
c. 20mL/kg NS
d. Epinephrine IV
20ml/kg NS bolus or Epi IM
Boy with a week of myalgias and fever. Presents with bilateral swelling and pain extending from the ear to the angle of the jaw. What medication? a. Amox-clav b. Analgesia and supportive management c. Dexamethasone d. IVIg
Analgesia and supportive management
A child at daycare bites another child and causes bleeding from a superficial bite. Both are immunized but their hepatitis B status is unknown. The next best step is:
a. Check Hep B serology
b. Give both the Hep B vaccine
c. HIV testing
d. Give both the Hep B immunoglobulin
- —-
a. Do HBV serology on both
b. Give oral clavulin prophylaxis to the bitten child
c. Check both for HBV surface Antigen and antibodies
d. Give Hepatitis B vaccine to both
Give both the Hep B vaccine
6 month old, mother with hepatitis C (antibody positive, HCV RNA positive). Babe is well with normal liver enzymes and negative anti-HCV antibody. What do you do?
a. Reassurance, no further testing needed
b. Check HCV RNA
c. Repeat serology in 6 months
d. Liver biopsy
Reassurance, no further testing needed