2018 Flashcards
In tuberculosis, what are two differences between the clinical presentation of early primary disease and reactivation disease? (2)
Primary: highest risk <4yo, risk of disseminated disease is higher. Reactivation: highest risk >10yo, low risk of disseminated disease.
What is the most sensitive screening test for tuberculosis in children under 2 years?
a. Chest XR
b. TST
c. IGRA
d. Blood culture
b: TST is more sensitive <2 and IGRA is always more specific
A 4 year old child was exposed to active pulmonary TB. They are asymptomatic. The chest x-ray is normal. A tuberculin skin test measures 3mm. What is the most appropriate management?
a. No treatment
b. Treat for latent TB infection with the standard four-drug regimen
c. Single drug prophylaxis for 8 to 10 weeks, then repeat TST, and treat if ≥5mm
d. No treatment at this time, repeat TST in 8 to 10 weeks, and treat if ≥5mm
c: because <5yo. Otherwise no prophylaxis.
Name 5 organs or tissues that can be involved in disseminated TB disease. (5)
Lungs, brain, retina, liver, spleen, joints, bone, bone marrow, muscle
Name 5 possible manifestations of reactivation TB disease. (5)
Cavitary pulmonary lesions, pleural effusions, osteoarticular infections, spleen abscess, liver abscess, CNS abscess, disseminated disease
List six “red flag” findings concerning for alternate diagnoses on history, physical exam, and initial investigations for a patient with presumed ITP. (3 total, 0.5 each)
B-symptoms, bone pain, recurrent thrombocytopenia, lack of response to treatment, lymphadenopathy, hepato/splenomegaly, signs of chronic disease, moderate-severe anemia, high or low WBC, high MCV, abnormal smear
Name two factors that will affect your decision of whether to choose active treatment or observation for a patient with ITP. (2)
Severity of bleeding, parental preference / risk tolerance level, child wanting to return to activities and sports (NOT absolute platelet count)
If choosing conservative management / observation for typical newly diagnosed ITP, name three essential parts of your followup plan. (3)
Physical examination for signs of bleeding, check CBC to follow platelets and other cell lines, advise to avoid contact sports or activities that may cause hits to the head, advise to avoid NSAID/ASA/any meds or herbal supplements with anti-platelet activity, continue regular appointments until counts have recovered
What are the five recommended elements of working with vaccine-hesitant parents? (5)
Keep them in your practice; identify parental concerns with presumptive, motivational interviewing; present risks/benefits with clear, effective language; manage immunization pain; discuss herd immunity / community protection.
Mnemonic: PPPPP (Practice they shouldn’t get kicked out of, Parental concerns / presumptive interviewing, Present the risks/benefits, Pain management, Protect the community)
Which of the following is the best tactic to employ with a vaccine-hesitant family?
a. Explaining to the family that you cannot provide medical care to the child if they choose not to immunize
b. Providing a list of vaccine concerns frequently raised by parents along with comprehensive rebuttals
c. Using a participatory approach when introducing the topic of the child’s routine vaccinations
d. Telling an emotionally powerful true story about vaccine-preventable illnesses
d: don’t introduce concerns not brought up by the family, use a presumptive not participatory approach
List two reasons why it is not advisable for parents to rely on “herd immunity” to protect their child from vaccine-preventable diseases. (2)
Outbreaks still occur which overwhelm herd immunity and generally by that time it is too late to vaccinate, some diseases eg tetanus have no herd immunity, choosing not to vaccinate puts others in our orbit at risk eg neonates and pregnant women
What term is currently preferred over “herd immunity”? (1)
“Community protection”
A patient presents to ED after a bee sting. In which situation(s) do you need to prescribe an EpiPen when the patient is well enough to go home?
a. Lip swelling, wheeze, and hypotension starting 10 minutes after being stung
b. Generalized urticaria starting 10 minutes after being stung
c. A 15cm-diameter area of swelling, erythema, and pruritus around the sting site that has been worsening since the sting 24 hours ago
d. A and B
e. A, B, and C
a: not needed for isolated cutaneous reactions as these do not presage life-threatening reactions in the future
A patient presents to ED with an anaphylactic reaction after a bee sting. You manage the patient appropriately in the ED with epinephrine followed by a period of observation. The patient is now well and ready for discharge home.
a) Aside from making a referral to an allergist, what are two important elements of your discharge plan for this patient? (2)
b) Name two reasons why is it necessary to refer the patient to an allergist. (2)
a) prescribe EpiPen, arrange for a serum tryptase when well, provide instructions on how to avoid stinging insects, anticipatory guidance on signs of anaphylaxis; b) to confirm anaphylactic allergy, to assess eligibility for venom immunotherapy
List three measures that a patient or family can use to avoid stinging insects. (3)
Do not walk barefoot outdoors, exercise caution when eating and drinking outdoors, avoid drinking from opaque cans or straws outdoors, wear gloves and long sleeves for gardening and a long sleeve shirt for play in high-risk areas, remove all insect nests around the home and call a professional for insect control or nest removal in confined or hard-to-reach spaces
Mnemonic: NOSES (Nest removal, Opaque cans, Shoes when outdoors, Eating carefully outdoors, Shirt)
A young woman in your clinic is asking about the difference between “typical use” and “perfect use” failure rates for contraceptives. What property of a contraceptive method is most important in determining its “typical use” failure rate? (1)
How user-dependent the method is
Describe the three tiers of contraceptive options for youth and give an example of each. (6)
First-tier: act over a long time period without needing any intervention; IUD/IUS
Second-tier: act over a shorter time period, require periodic intervention; OCP, patch, Nuva, DP
Third-tier: act only at the moment and depend on individuals’ motivation, skill, and timing; condoms, withdrawal, rhythm, diaphragm, cap, sponge
Name the major health complication associated with Depo-Provera (1) and two recommendations you might make to a patient starting it in order to reduce the risk of this complication (2).
Bone demineralization; optimize Ca++ and VitD intake, weight-bearing exercise, reduce caffeine/alcohol/tobacco use
When prescribing an oral contraceptive, which of the following is true?
a. Close followup — providing an OCP prescription for only two to three months at a time and requiring the patient to return for refills — improves adherence to the OCP and decreases the overall rate of contraceptive failures
b. It is important to be screened for pregnancy before starting OCPs because they can be teratogenic in early pregnancy
c. If breakthrough bleeding occurs during ‘extended use’ or ‘continuous use’ OCP, the pill should be stopped for 4 to 7 days or else the breakthrough bleeding may continue indefinitely
d. The risk of stroke or VTE is approximately doubled by using combined oral contraceptives
d: yearlong prescriptions improve adherence and outcomes, OCPs are not teratogenic, breakthrough bleeding stops on its own
List three medications that may be used in the management of neonatal abstinence syndrome. (3)
Morphine, methadone, clonidine, phenobarbital, buprenorphine
Which of the following statements is false?
a. 50-75% of babies born to mothers using opioids will require treatment for opioid withdrawal
b. Symptoms of neonatal opioid withdrawal generally start within the first 72h of life, but may not present until day 5-7 of life if the mother has been on methadone or buprenorphine
c. A trained pediatric team, rather than the routine healthcare provider, should be present at the delivery when the mother is known to have been using opioids
d. Preterm babies are probably less likely to experience neonatal opioid withdrawal
c: routine is fine unless other indications
List six signs/symptoms of neonatal opioid withdrawal. (6)
High pitched cry, short sleep cycles, hyperactive Moro reflex, tremor, increased tone, myoclonic jerks, convulsions/seizures, diaphoresis, increased temperature, yawning, mottling, nasal stuffiness or sneezing, nasal flaring, tachypnea, excessive sucking, poor feeding, regurgitation, loose stools
Name the three essential elements of informed consent. (3)
Capacity, fully informed, free from coercion.
What is the difference between ‘consent’ and ‘assent’, and why is this distinction relevant to the pediatric population? (2)
Assent: patient agrees to the proposal but without true consent (may be incompletely informed, may be coerced, may not be capable of consent). Relevant because many of our patients are not able to give consent, yet it is important to still get their assent when possible