2017 biochem shorts Flashcards

1
Q

What happens to RBC if they are put in saline solution0.3% solution?

A: RBC disintegrates(membrane disruption,hemolysis)

B:RBC shrinks(plasmolysis)

C: The fate of RBC depends on the ph of the millieu

A

A

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2
Q

Which molecule is mainly able to deviate of pH in alkalosis?

A: H2CO3

B:HCO3-

C:HPO4-

D: ALL

A

A

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3
Q

What is the average concentration of k+ in the intracellular compartment of K+under physiological conditions?

A

95mmol/l

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4
Q

componets of cephalin?

A

diaglycerol + 1 phosphate +1 cholamine

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5
Q

what sentence is false about the membrane forming cholesterol?

a: it is located on the outer side of the membrane, associated to polar hydrophillic part of phospholipid bilayer

B: Increase of proportion > membrane rigidity

C: This lipoid belongs to compounds with steroid ring

D: all are true

A

all are true

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6
Q

What is true about facilitated diffusion?

A: glucose is transported on the basolateral side of enterocytes by it

B: TRANSPORTER (carrier molecule is needed)

C: IT DOESNT NEED ENERGY

D: all true

A

all true

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7
Q

Which following material is transported typically by simple diffusion through membrane?

A: Co2

B:NA+

C:Glucose

D:all

A

all

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8
Q

Which amino acid contains Sulphur?

A

Cysteine

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9
Q

Which aminos acid side chain(r group) contain Nitrogen?

A

Lysine

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10
Q

What is a secondary structure of proteins?

A

Regularly repeating units of polypeptide chains

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11
Q

Which protein is a hemoprotein?

catalase

casein

large subunit of na k pump

all

A

Catalase

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12
Q

How does the number of cross linkages change between tropocollagen fibres with age?

A

Increase

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13
Q

The substrate specifity is determined by which part of the enzyme?

A

substrate binding site

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14
Q

Km value for enzyme 10mmol/l. what is true for enzymes?

A

if 10mmol/l substrate concentration, the reaction velocity is larger than half of the maximal speed

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15
Q

What answer is false about allosteric enzyme inhibition?

A

the inhibitor attaches to the substrate binding site

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16
Q

Which enzyme is produced by the inactive zymogen?

succinate dehydogenase

pepsin

xanthine oxidase

all

A

all

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17
Q

which enzyme belongs to the enzyme class oxidoreductase?

Phosphoglucomutase

Dna ligase

amylase

all answers are false

A

all false

18
Q

What are the true components of AMP?

A

Adenine+ ribose +phosphate

19
Q

Promary structure of Dna?

A

sequence of nucleotides building DNA

20
Q

Which one is composed of RNA IN ITS CHEMICAL STRUCTURE?

A

Primer

21
Q

What is false about replication?

A:the DNA polymerase 3 links the first nucleotide tobe built to free 3’ end of primer in prokaryotes

B: the replication of the leading strand of the DNA is continous

C: Helicases is needed for iniation of replication

D: all false

A

the replication of the leading strand of the DNA is continous

22
Q

What is necessary forthe operation of DNA polymerase 3?

A

Ribonucleoside 3p (NTPS)

23
Q

What is the cause of frame shift?

A

deletion mutation

24
Q

What is necessary for initiation of transcription in prokaryotes?

DNA dependent Rna polymerase

RHo factor

RNA template

all

A

all of them

25
Q

Transcription of what type of RNA is done by RNA polymerase 3 in eukaryotes?

A

tRNA

26
Q

What is 5’ capping?

A

7 methyl guanosine gap attached to 5’ end mRNA

27
Q

What is necessary for activation of amino acids?

A

ATP

28
Q

which processes require energy?

Binding new aminoacyl tRNA to a binding site

operation of a peptidyl transferase

disconnected freed+ RNA from ribosome

all

A

all

29
Q

What is catalysed by translocase during elongation translation

A

Translocation peptidyl tRNA from A to P binding site

30
Q

Which Dna fragments is recognised by restriction endonucleases?

A

palindrom sequence

31
Q

What is the function of vectors in genetic engineering

A

Transport of appropriate gene in host cell

32
Q

which is necesscary for amplification of Dna using pcr method?

deoxyribonucleasetriosphosphate (dntps)

taq polymerase

primer

all true

A

all true

33
Q

which one is a ketose?

A

Fructose

34
Q

characteristic of linolenic acid

A

18 carbons 3 double bonds 9 12 15

35
Q

which metabolic process dont happen in liver?

A

Ketolysis

36
Q

lack of enzyme is allontoin not produced in birds?

A

uricase

37
Q

Which cell is able to produce hyalurodinase?

A

Sperm cell

38
Q

White adipose tissue?

ppp

ketogenesis

bile acid synthesis

all

A

pentose phosphate cycle

39
Q

which molecule is responsible for energy in muscles?

A

Creatine phosphate

40
Q

what molecule can get through the blood brain barrier?

A

Glucose