2016

Question 1

What Drug is used for HIV therapy?

Answer 1

Saquinavir

Question 2

What is an effect of Benign tumours?

Answer 2

Pressure

Question 3

What drug is only used in the treatment of UTIs

Answer 3

Nitrofurantoin

Question 4

What is given intravenously when treating MRSA

Answer 4

Vancomycin

Question 5

What does the pathogenesis of systemic type 3 hypersensitivity require?

Answer 5

Immune complex formation

Question 6

Serious infection with a Gram negative organism such as E-coli indicates treatment with what intraveneously?

Answer 6

Gentamicin

Question 7

What is a teratoma more commonly?

Answer 7

Benign in women, malignant in men

Question 8

serious systemic fungal infection indicates treatment with intravenous what?

Answer 8

Amphotericin B

Question 9

What are Neutrophil polymorphs?

Answer 9

A major component of the acute inflammatory response

Question 10

In terms of the cell cycle

Answer 10

cytokinesis is the last step in the production of daughter cells

Question 11

what syndrome is not the result of an additional chromosome?

Answer 11

Turner syndrome

Question 12

What do fibroblasts do?

Answer 12

produce collagen

Question 13

What does histamine do?

Answer 13

relaxes vascular smooth muscle in acute inflammation

Question 14

What does hypoxia do?

Answer 14

• lack of oxygen - impedes tissue healing

Question 15

In mitosis which phase consists of chromosomes aligning at the equator of the cell?

Answer 15

metaphase

Question 16

Chromosomes become visible as a result of which step of mitosis?

Answer 16

Prophase

Question 17

Why is GTN administered by the sublingual route?

Answer 17

to avoid first pass metabolism

Question 18

Which DNA fragments analysis method does not require an electric field?

Answer 18

PCR

Question 19

What is a mutation that causes a protein to be finished prematurely called?

Answer 19

Nonsense

Question 20

In the process of transcription and translation what is the adapter molecule that acts between the coded amino acid and the mRNA?

Answer 20

tRNA

Question 21

In DNA replication what is a true fact to remember?

Answer 21

The leading strand is formed continuously

Question 22

What are the types of ADR?

Answer 22

Augmented 
Bizarre
Chronic
Delayed
End of treatment
Failure of treatment

Question 23

What enzyme is involved in phase 1 drug metabolism?

Answer 23

CYP1A2

Question 24

When is only one side of DNA replicated

Answer 24

Transcription

Question 25

What is the process that requires cooperation and coordination between mRNA tRNA and rRNA

Answer 25

Protein synthesis

Question 26

mRNA is used to form an amino acid sequence during the process of?

Answer 26

Transcription

Question 27

What does mitosis produce?

Answer 27

produces diploid cells from diploid cells

Question 28

What causes rubor and calor in acute inflammation?

Answer 28

Increased blood flow

Question 29

What drug should be used to treat an unknown gram negative bacteria?

Answer 29

gentamicin

Question 30

What does meisosis produce?

Answer 30

Produces haploid cells from diploid cells

Question 31

What does fertilisation produce?

Answer 31

produces diploid cells from haploid cells

Question 32

Where is the primary site of protein synthesis

Answer 32

Ribosomes

Question 33

The X chromosome is?

Answer 33

Transmitted by mothers to both son and daughter transmitted by fathers to daughters but not sons

Question 34

The Y chromosome?

Answer 34

Is transmitted only by fathers

Question 35

Retinoblastoma is caused by what?

Answer 35

Is caused by a loss of tumour suppressor gene

Question 36

what is an adenocarcinoma

Answer 36

Malignant rumour of glandular epithelium

Question 37

What drug is used for both HERPES and Varicella VZV

Answer 37

aciclovir

Question 38

What drug is used topically or in oral suspension for serious fungal infection therapy?

Answer 38

Nystatin

Question 39

What drug can be used to treat Beta-lactamase producing Staph aureus

Answer 39

Flucloxacillin

Question 40

What drug is the best choice for IV treatment of serious pneumococcal, meningococcal and strep pyogenes infection as well as most other Gran positive infections?

Answer 40

Benzylpenicillin

Question 41

what does the pathogenesis of systemic type IV hypersensitivity require?

Answer 41

Gamma-interferon production

Question 42

What are Giant Cells?

Answer 42

usually a major component of granulomatous inflammation

Question 43

What does Serotonin do?

Answer 43

Produces vasoconstriction in inflammation

Question 44

How can amphotericin B be administered?

Answer 44

oral and IV

Question 45

How can Beta lactamase resistance be combatted?

Answer 45

can be combatted with co-amoxiclav

Question 46

What is ciprofloxaci?

Answer 46

it is a fluoroquinolone that inhibits nucleic acid synthesis

Question 47

What drug inhibits purine synthesis

Answer 47

Trimethoprim

Question 48

Name the major eukaryotic histone

Answer 48

H1, H2A, H2B, H3, H4

Question 49

How may chromosomes do you expect to label in each karyotype when using FISH to probe for X Chromosomes in Turner syndrome patient?

Answer 49

1

Question 50

Which is the most suitable method of testing whether a healthy individual is a carrier forsickle cell anaemia?

Answer 50

Karyotyping