2014 RC Flashcards

1
Q

Rifampin mechanism of action

A

inhibits DNA dependent RNA polymerase

used in TB

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2
Q

MOA of 5-FU

A

pyrrimidine analog
works through inhibition of thymidylate synthase

aka blocks the synthesis of thymidine

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3
Q

Ant. cerebral artery supplies

A

medial portions of frontal and

superior medial parietal

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4
Q

pons and cerebellum derive from

A

rhomboencephalon->gives rise to metencephalon

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5
Q

how sulfonamides work

A

antibacterial sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthetase (DHPS), an enzyme involved in folate synthesis. Sulfonamides are therefore bacteriostatic and inhibit growth and multiplication of bacteria, but do not kill them.

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6
Q

vagus mediated secretions in the GI system

A
  • strongest stimulant of H+ secretion

- also pepsinogen, mucus, HCo3, and intrinsic factor

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7
Q

what is the crista terminalis

A

-Vertical ridge between vena cavae orifices.
■ Sinoatrial (SA) node is located here.
■ Junction of sinus venosus and the heart in the developing embryo.

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8
Q

chordae tendinae and papillary muscles…

A

prevent valves from going into atria

DO NOT help valves close

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9
Q

what causes thyroid enlargment in graves

A

immunoglobulin antbodies to TSH receptors in thyroid

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10
Q

gas gangrene bacteria

A

clostridium perfringes

lecinithinase -destroy memrbanes

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11
Q

crypts of leuberkuhn are where

A

epithelial lining of intestine and colon

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12
Q

moa tetracyclin

A

30S subunit of microbial ribosomes. It inhibits protein synthesis by blocking the attachment of charged aminoacyl-tRNA to the A site on the ribosome. Thus, it prevents introduction of new amino acids to the nascent peptide chai

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13
Q

glucagon- what it does

A
increase BGL
glycogenolysis in LIVER NOT MUSCLE
inc. free fatty acids
AA breakdown
urea production
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14
Q

phosphoglycerate kinase

A

1-3 bisphosphoglycerate to 3- phosphoglycerate

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15
Q

what abducts the vocal cords

A

posterior cricoarytendoid

innervated by recurrent larngyeal

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16
Q

nucleus that makes adh

A

supraoptic