2. The Diseased Periodontium Flashcards

1
Q

Classification of Periodontal Diseases and Conditions*
▪ Gingival Diseases
• Plaque-Induced Gingival Diseases
• Non-Plaque-Induced Gingival Lesions

▪ Chronic Periodontitis
▪ Aggressive Periodontitis
▪ Periodontitis as a Manifestation of Systemic Disease
▪ Necrotizing Periodontal Diseases
▪ Abscesses of the Periodontium
▪ Periodontitis Associated with Endodontic Lesions
▪ Developmental/Acquired Deformities and Conditions

*____ for the Classification of Periodontal Diseases

A

1999 International World Workshop

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2
Q

Classification of Periodontal Diseases and Conditions

▪ Gingival Diseases
• ____-Induced Gingival Diseases
▪ ____ Periodontitis
▪ ____ Periodontitis

A

plaque
chronic
aggressive

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3
Q

Plaque-Induced Periodontal Diseases

Gingivitis - ____ of the gingiva
Periodontitis - inflammation and destruction of the ____

Attachment apparatus: ____ & ____ and ____

A

inflammation
attachment apparatus

cementum
alveolar bone
PDL

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4
Q

Structure of the Periodontium

Can only see ____ histologically

A

PDL

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5
Q

Plaque-Induced Gingivitis

Mild > Moderate > Severe

Moderate > fair amount of ____
Severe > ____, ____ bleeding

____ classification

A

edema
edematous
spontaneous
subjective

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6
Q

Plaque-Induced Periodontitis

Severity can be based on: ____ levels (measurement you make with periodontal probe), look at extent of ____ relative to length of root (<25% is mild, 25-50% is moderate, >50% is advanced)

Need ____ in order to make classification

____ vary from individual to individual, and from anterior to posterior teeth

A

attachment
bone loss
PA radiographs
roots

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7
Q

Page and Schroeder Lesions

Defined four phases of disease: ____, ____ and ____; and then an ____ lesion: periodontitis

A

initial
early
established
advanced

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8
Q

Page and Schroeder Histologic Stages of Gingivitis and Periodontitis

Initial Lesion (Clinical Health)

  • Slightly ____ vascular permeability and vasodilation.
  • ____ flows out of the sulcus.
  • Migration of leukocytes, primarily PMNs, in relatively ____ numbers through the gingival connective tissue, across the junctional epithelium and into the sulcus.

Early Lesion (Early Gingivitis)

  • Increased vascular permeability, vasodilation and ____ flow.
  • ____ numbers of infiltrating leukocytes (mainly PMNs and lymphocytes.
  • Degeneration of ____.
  • Collagen ____, resulting in collagen depleted areas of the connective tissue.
  • Proliferation of the ____ and ____ epithelium into collagen-depleted areas.

No one has inflammation-____ periodontium > neutrophils migrate into JE into the gingival sulcus > low-level inflammatory reaction that cannot be seen clinically, but can be seen histologically

A

elevated
GCF
small

GCG
large
fibroblasts
degradation
junctional
sulcular

free

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9
Q

Page and Schroeder Histologic Stages of Gingivitis and Periodontitis

Established Lesion (Established Gingivitis)

  • ____ inflammatory cell infiltrate (PMNs, plasma cells, lymphocytes).
  • Accumulation of inflammatory cells in ____ tissue.
  • Elevated release of ____ and the ____ contents from PMNs.
  • Significant collagen depletion and epithelial proliferation.
  • Formation of ____ epithelium containing large numbers of PMNs.

Advanced Lesion (Periodontitis)

  • Predominance of PMNs in the ____ epithelium and pocket.
  • Dense inflammatory infiltrate in connective tissues that is made of predominantly ____ cells.
  • Apical migration of the ____ epithelium to preserve an intact epithelial barrier.
  • Continued collagen breakdown resulting in large areas of collagen depleted connective tissue.
  • ____ resorption of bone.

Established = ____ from of periodontitis

A
dense
connective
matrix metalloproteinases (MMPs)
lysosomal contents
pocket
pocket
plasma
junctional
osteoclastic
severe
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10
Q

Page and Schroeder Lesions

Initial lesion > Early lesion > Established Lesion > Advanced Lesion

No radiographic evidence of ____!

A

alveolar bone loss

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11
Q

Healthy Periodontium

Lines represent the ____ bundles of the gingival CT

A

principal fiber

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12
Q

Healthy Periodontium

The measurement from the gingival margin to the most coronal aspect of the ____ is equal to the ____ depth.

  • Histologically, the mean gingival sulcus depth is ____ mm.
  • Clinically, the gingival sulcus depth ranges from ____ to ____ mm in health.

____ > presence of pathology; gingival sulcus is normal

A
JE
gingival sulcus
0.6
1
3

pocket

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13
Q

Healthy Periodontium

Epithelial Attachment of Gingiva (mean of ____ mm)
Connective Tissue Attachment of Gingiva (mean of ____ mm)

Biologic Width = Epithelial Attachment + Connective Tissue Attachment = mean of ____ mm

CT only serve purpose of attaching ____ to the teeth

JE ends at the ____

A

1.0
1.0
2.0
soft tissues
CEJ

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14
Q

Health Periodontium

Histology:
- Intact junctional epithelium without ____.
- Intact connective tissue attachment of the gingiva to cementum via ____.
- Alveolar bone crest positioned approximately ____ mm apical to the
cementoenamel junction.
- Sparse number of neutrophils transmigrating from the vascular plexus through the junctional epithelium into the sulcus.

Clinical Findings:

  • Gingiva is ____ (can be ____).
  • Clearly defined ____ junction.
  • Gingiva is ____.
  • ____ gingival margins.
  • Gingiva is ____.
  • Probing depths of ____ to ____ mm without bleeding on probing

Radiographic Findings:

  • Clearly defined alveolar bone crests positioned approximately ____ mm apical to the cementoenamel junction.
  • Clearly defined ____.
  • Absence of ____ defects.
  • Intact ____ bone.

____ = spaces bt multi-rooted teeth are filled with defined bone

A

rete ridges
gingival fiber bundles
2

coral pink
pigmented
mucogingival
firm
1
3

2
lamina dura
infrabony
furcal

infurct

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15
Q

Periodontal Probing of the Healthy Periodontium

The histologic sulcus has a mean depth of ____ mm while clinically, probing depths range from ____ to ____ mm due to penetration of the junctional epithelium (up to ____ of its length).

We do not have sufficient ____ sensation to stop at the mean depth of gingival sulci; that’s why the depths are ____ than what they actually are

A

0.6
1
3
50%

tactile
deeper

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16
Q

The Early Lesion: Mild Gingivitis

Clinical Findings:
- Marginal gingiva is slightly \_\_\_\_ and edematous.
- Slightly \_\_\_\_ gingival margins.
- Increase in probing depth (typically less than \_\_\_\_ mm) and minimal
\_\_\_\_.
- Clearly defined \_\_\_\_ junction. 
- Gingiva is \_\_\_\_.
Radiographic Findings:
- No \_\_\_\_ relative to health.
A
erythematous
rounded
1
BOP
mucogingival
stippled
changes
17
Q

The Early Lesion: Moderate Gingivitis

Clinical Findings:
- Overlaps with mild gingivitis; no \_\_\_\_ dividing line.
- Increased \_\_\_\_ and edema.
- \_\_\_\_ gingival margins.
- Increase in probing depth (typically less than \_\_\_\_ mm) with \_\_\_\_.
- Loss of \_\_\_\_.
- Clearly defined \_\_\_\_ junction.
Radiographic Findings:
- No \_\_\_\_ relative to health.
A
clear cut
erythema
rounded
1
BOP
stippling
mucogingival
changes
18
Q

The Early Lesion: Mild to Moderate Gingivitis

Histology:
- Lateral proliferation of junctional epithelium yielding additional ____.
- ____ blood vessels.
- Increased numbers of transmigrating PMNs in the JE.
- Accumulation of inflammatory cells (PMNs and lymphocyte) cells immediately
subjacent to the ____ at the site of ???
- Cytopathic alterations of ____.
- Intact connective tissue attachment of the gingiva via ____.
- Alveolar bone crest positioned approximately ____ mm apical to the CEJ.

A
rete ridges
dilated
JE
resident fibroblasts
gingival fiber bundles
2
19
Q

Gingival Pocket

Gingival Pocket – deepening of the ____ resulting primarily from an increase in the bulk of the ____ without ____ of the junctional epithelium or appreciable destruction of the underlying connective tissue.

Coronal aspect of JE ____ from surface of tooth, and ____ migration of gingival margin > change in ____ depth

A

gingival sulcus
gingiva
apical migration

detaches
apical

coronal

20
Q

Periodontal Probing of Mild to Moderate Gingivitis

Relative to health, there may be an ____ in probing depth detected in patients with mild gingivitis due to penetration of the JE to within ____ mm of its apical aspect by the probe.

Inflamed CT lack ____ when compared to normal health

Compromised ____ > increase in probing depth

A

increase
0.1
strength

attachment

21
Q

The Established Lesion: Severe Gingivitis

Clinical Findings:

  • Tissue may have a ____ color.
  • ____ bleeding.
  • Increased erythema and edema.
  • ____ of marginal and interproximal gingiva.
  • Increase in depth of gingival ____ with bleeding on probing.
  • Further loss of ____.
  • Clearly defined ____ junction.

Radiographic Findings:
- No ____ relative to health.

A
cyanotic (bluish)
spontaneous
"overgrowth"
pockets
stippling
mucogingival

changes

22
Q

The Established Lesion: Severe Gingivitis

Histology:

  • Further lateral proliferation of junctional epithelium yielding additional ____.
  • Formation of ____ epithelium.
  • Accumulation of ____ cells and ____ in the connective tissue.
  • Leukocyte ____ at plaque front.
  • Severe ____ damage and further collagen loss.
  • Further loss of ____ supporting the marginal gingiva
  • Intact connective tissue attachment of the gingiva via ____.
  • Alveolar bone crest positioned approximately ____ mm apical to the CEJ.

Inferior aspect of JE doesn’t ____, still remains at the CEJ

During periodontitis, the ____ structure moves apically (including the inferior aspect of the JE)

A
rete ridges
pocket
plasma
immunoglobulin
"wall"
fibroblast
collagen
gingival fiber bundles
2

move
whole

23
Q

Gingival Pocket

Gingival Pocket – deepening of the gingival sulcus resulting primarily from an increase in the bulk of the ____ without apical migration of the junctional epithelium or appreciable destruction of the underlying connective tissue.

____ pushes the gingival margin upwards

A

gingiva

edema

24
Q

Periodontal Probing of Severe Gingivitis

Relative to health, mild and moderate gingivitis, there may be an additional ____ in probing depth detected in patients with severe gingivitis due to:

  • ____ resulting in coronal migration of the gingival margin.
  • probe penetration through the ____.
  • The inferior aspect of the epithelial attachment does not move ____!

Severe gingivitis > penetrates the entire epithelium, and the intact ____ end up halting the probing depth

A

increased
edema
junctional epithelium
apically

principal fiber bundles

25
Q

The Advanced Lesion: Periodontitis

Clinical Findings: Highly Variable
- Presence of \_\_\_\_ and calculus.
- Gingival \_\_\_\_ and edema.
- Absence of \_\_\_\_.
- \_\_\_\_ bleeding and/or \_\_\_\_. 
- Gingival \_\_\_\_.
- Tooth \_\_\_\_ and/or fremitus.
- Loss of \_\_\_\_.
- The \_\_\_\_ junction may not be well defined.
- Probing depths of \_\_\_\_ mm or greater with bleeding on probing.
on probing. 
- Others

Smoking has a ____ factor

A
plaque
erythema
papillae
spontaneous
suppuration
recession
mobility
stippling
mucogingival
4

vasoconstrictive

26
Q

The Advanced Lesion: Periodontitis

Radiographic Findings: Highly Variable

  • ____ calculus.
  • ____ bone loss.
  • Bone loss in ____.
  • Widening of ____.
  • Others
A

subgingival
crestal
furcations
PDL

27
Q

The Advanced Lesion: Periodontitis

Histology:
- ____ proliferation of the pocket (junctional) epithelium.
- ____ of the pocket (junctional) epithelium.
- Periodontal ____ formation.
- ____ blood vessels.
- Massive inflammatory infiltrate predominated by ____ cells.
- Further loss of collagen supporting the marginal gingiva including breakdown of the ____ making up the connective tissue attachment of the
the gingiva to the teeth.
- ____ resorption.

A
apical
ulceration
pocket
dilated
plasma
gingival fiber bundles
alveolar
28
Q

Periodontal Pocket

Periodontal Pocket (True Pocket) – a pathologically deepened ____ resulting from ____ migration of the junctional epithelium along the root as the ____ is detached as a result of a disease process.

____ is degraded in periodontitis

Edema causing the ____ migration of the gingival margin

Most increase in probing depth is due to the ____ part of the JE and the movement of the entire ____…

A

gingival sulcus
apical
PDL

CT attachments

coronal
coronal
JE

29
Q

Periodontal Pocket

____ of the junctional epithelium is likely to contribute to accumulation of bacteria and their products in the gingival connective tissue.

Presence of ____

Epithelium does not have vasculature; if you see bleeding coming from there, then the integrity of the ____ surface is comprised > an ulcerated epithelium

If this is in a periodontal pocket, referred to as a ____ epithelium (this is the explanation for BOP)

More common to have bleeding on periodontal pockets…

Disintegrating epithelial layer > ____ products can infiltrate the connective tissue > interact with innate and adaptive immune cells > ____ process > ____ > bone-resorption

JE acts as an important form of ____ immunity (as a physical barrier)

A

ulceration
RBC
epithelial
pocket

bacterial
inflammatory
osteoclastogenesis

innate

30
Q

Pocket Epithelium

Cells are undergoing ____

A

apoptosis/necrosis

31
Q

The Advanced Lesion: Periodontitis

The body appears to always protect the alveolar bone by covering it with healthy ____ (approximately ____ mm in thickness).

Perio probe sits above this ____

A

connective tissue
1
structure

32
Q

Periodontal Probing of Periodontitis

The probe penetrates through the junctional epithelium and inflamed connective tissue until resistance occurs when it encounters healthy ____.

Can have measurements over ____mm and not have ____ loss

> 5mm: patient will have some ____ loss (with some exceptions, like ____)

A
connective tissue
4
attachment
attachment
drug-induced gingivitis
33
Q

Suprabony versus Infrabony Periodontal Pockets

Suprabony Pocket:
The base of the pocket is ____ to the level of the underlying bone.
- Bone crest must absorb ____ and ____

Infrabony Pocket:
The base of the pocket is ____ to the level of the adjacent bone.
- Bone crest has ____ bone less

____ > gingival overgrowth

Position of base of pocket relative to bone crest…

A

coronal
apically
uniformly

apical
vertical

pseudopocket

34
Q

Periodontal Pockets

Suprabony Pockets
The extent of bone loss is relatively ____. The pattern of bone loss is referred to as being ____.

Infrabony Pockets
The extent of bone loss is ____. The pattern of bone loss is referred to as being ____.

A

uniform
“horizontal”

variable
“vertical”