2) Terminology Flashcards

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1
Q

Stratum corneum

A
  • Consists of terminally differentiated keratinocytes (corneocytes)
  • Outermost layer
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2
Q

Stratum lucidum

A
  • Thin, clear layer which is translucent (volar skin)
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3
Q

Stratum granulosum

A
  • Thin layer of keratinocytes with keratohyalin granules
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4
Q

Stratum spinosum

A
  • Appears “spiny” when stained with H & E
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5
Q

Stratum basale

A
  • Deepest layer

- Consisting of keratinocytes, melanocytes, langerhans cells, and merkel cells

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6
Q

Papillary layer

A
  • Directly beneath the epidermis
  • Contains papillae which house looped capillaries and corpuscles
  • Lose areolar connective tissue
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7
Q

Reticular layer

A
  • Deeper layer which contains vessels, glands, etc.
  • Connective tissue is dense and irregular
  • Orientation of collagen fibers contributes to skin tension lines (Langer’s lines)
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8
Q

Macule

A
  • Flat, colored lesion
  • Less than 2cm
  • Not raised above the skin
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9
Q

Patch

A
  • Larger, flat colored lesion
  • Greater than 2cm
  • Differs from macule only in size
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10
Q

Papule

A
  • Small, solid lesion
  • Less than 0.5cm in diameter
  • Raised above the surface of surrounding skin and is palpable
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11
Q

Nodule

A
  • Larger, firm lesion
  • 0.5 to 5cm
  • Raised above the surface
  • Differs from papule in size
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12
Q

Tumor

A
  • Solid, raised growth

- Varies in size and depth

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13
Q

Plaque

A
  • Large, greater than 1cm
  • Flat-topped, raised lesion
  • Edges may be distinct or blend to surrounding skin
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14
Q

Vesicle

A
  • Small, fluid-filled lesion above the surrounding skin

- Measures less than 0.5cm

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15
Q

Pustule

A
  • Vesicle filled with leukocytes
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16
Q

Bulla

A
  • Fluid filled lesion above the surrounding skin measuring greater than 0.5cm in diameter
17
Q

Wheal

A
  • Raised, erythematous, edematous papule or plaque

- Brought on by temporary vasodilation and vasopermeability

18
Q

Telangiectasia

A
  • Dilated, superficial blood vessel
19
Q

Lichenification

A
  • Distinctive thickening of skin

- Characterized by accentuated skin-fold markings

20
Q

Scale

A
  • Excessive accumulation of stratum corneum
21
Q

Crust

A
  • Dried exudate of body fluids which are either serous (yellow) or hemorrhagic (red)
22
Q

Erosion

A
  • Loss of epidermis without the loss of associated dermis
23
Q

Ulcer

A
  • Loss of epidermis and at least a portion of the underlying dermis
24
Q

Excoriation

A
  • Linear, angular erosion that may be covered by crust

- Caused by scratching

25
Q

Atrophy

A
  • Loss of substance which may appear as a depression of intact epidermis (dermal atrophy) or shiny, delicate, wrinkled lesions (epidermal atrophy)
26
Q

Scar

A
  • Fibrotic change in the skin secondary to trauma or inflammation
  • May be erythematous, hypo/hyperpigmented
27
Q

Alopecia

A
  • Hair loss which may be partial or complete
28
Q

Annular

A
  • Describes a ring shaped lesion
29
Q

Cyst

A
  • Soft, raised, encapsulated lesion

- Filled with liquid or semi-solid content

30
Q

Herpetiform

A
  • Refers to grouped lesions
31
Q

Lichenoid

A
  • Violacious to purple

- Polygonal lesions that resemble those seen in lichen planus

32
Q

Milia

A
  • Small, firm, white papules filled with keratin
33
Q

Morbilliform

A
  • Generalized, small erythematous macules and/or papules like that of measles
34
Q

Nummular

A
  • Coin shaped lesions
35
Q

Poikiloderma

A
  • Refers to skin that demonstrates variegated pigmentation, atrophy, and telangiectases
36
Q

Polycyclic

A
  • Configuration of skin lesions formed from coalescing rings or incomplete rings
37
Q

Pruritis

A
  • Sensation that elicits the desire to scratch