2- Synaptic Plasticity Flashcards

1
Q

A student is studying the nerve conduction velocity …… and the synaptic transmission occurs with central delay of 1.5 msec , calculate the number of synapses:

A

1.5 X2 = 3 synapses

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2
Q

A student is studying nerve conduction velocity …… calculate the central delay in pathway contain 3 synapses:

A

3\2 = 1.5 msec

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3
Q

Which of the following is a short and long term from pd placiticity ?

A

Sensitization

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4
Q

Which of the following causes loss of consciousness ?

A

interruption of cerebral circulation for 3-5 seconds

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5
Q

Which of the following causes irreversible brain damage?

A

interruption of cerebral circulation for 3-5 mints

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6
Q

Which of the following increases the synaptic transmission?

A

Hypocalcemia

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7
Q

Both hyperglycemia and hypoglycemia result in coma, explain.

A
  • Hypoglycemia: Glucose is the preferable fuel of the brain, so hypoglycemia inhibits synaptic transmission.
  • Hyperglycemia: increase the ketone bodies, causes acidosis result in increase in ionized Ca and decreases synaptic transmission
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8
Q

What are the characters of synaptic transmission?

A

1- Forward directions
2- Synaptic delay
3- Fatigues
4- Synaptic plasticity

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9
Q

What is the synaptic delay?

A

0.5 msec/synapse

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10
Q

What is the mechanism of the fatigue?

A

1- Exhaustion of pre synaptic vesicles due to repetitive stimulation
2- Depletion of neurotransmitters
3- Inactivation of post synaptic receptor (Down-regulation)
4- Gradual inactivation of the channels

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11
Q

The synaptic plasticity represents forms of?

A

Learning and memory

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12
Q

Forms of Synaptic plasticity?

A

1- Short (PTP, Habitation)
2- Long (LTP, Sensitisation)
3- LTD

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13
Q

The post tetanic potentiation is the basic mechanism for?

A

Immediate memory

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14
Q

What is the ionic basis of the post tetanic potentiation ?

A

Accumulation of Ca++ in the pre synaptic neurons

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