2 Skin & Structures

Question 1

The epidermis has 5 layers: _________ __________, stratum lucidum, stratum granulosum, stratum spinosum, and __________ ____________.

Answer 1

stratum corneum; stratum germinativum

Question 2

What are the cells of the dermis?

Answer 2

Keratinocytes, desmosomes, melanocytes, Langerhans Cells.

Question 3

What are 3 functions of epidermis?

Answer 3

1 barrier to toxins & microorganisms, 2 prevent water loss, 3 repel water

Question 4

Which skin layer contains nerves, sweat glands, sebaceous glands, and hair follicles?

Answer 4

Dermis

Question 5

Describe the Extraclular Matrix (ECM).

Answer 5

The largest component of dermis, gel-like matrix produced by surrounding cells, made of sugars & protein ( collagen & elastin), supports regulates lubricates and transports.

Question 6

What are the function of dermis?

Answer 6

Nourish epidermis, protect from mechanical injury and microorganisms, sense environment, thermoregulation.

Question 7

The cells of the dermis are MACRPHAGES, _____ cells, ___________, nerves, and ___________ cells.

Answer 7

mast; fibroblasts; Langerhans

Question 8

RBC’s - also known as __________- have a life expectancy of 120 days and are measured as ___ ________/________.

Answer 8

erythrocytes; a percentage/hematocrit.

Question 9

What are the two most common types of WBC’s?

Answer 9

Lymphocytes [ID foreign bodies and make designer antibodies] and
Neutrophils [most common, phagocytic, first responders to site of infection]

Question 10

Describe platelets.

Answer 10

Sticky cells that help prevent bleeding and are crucial to clot development by two steps (adhesion to wound site then activation of binding together); normal count is 150,000 to 400,000 per cu/ml.

Question 11

The pH of normal skin is…

Answer 11

slightly acidic at 4 to 5.5.