2. Respiratory Physiology Flashcards

1
Q

All organisms require oxygen which has to be?

A

derived or removed from some respiratory medium.

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2
Q

What is a respiratory medium?

A

The source of oxygen for animals

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3
Q

The main respiratory media are

A
  • Air
  • Freshwater
  • Salt water
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4
Q

What is the respiratory surface?

A

the area or space where the gas exchange takes place.

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5
Q

Respiratory surfaces should have what?

A

-Larger surface to volume ratio
-moist inner surface
-thin wall in contact with blood capillaries

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6
Q

Examples of respiratory surfaces

A

-external gills
-internal gills
-lungs

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7
Q

What is gaseous exchange?

A

the supplying of oxygen for cellular respiration and the disposing of carbon dioxide.

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8
Q

How do organisms obtain oxygen from the medium (the source of oxygen)?

A

the organism must be able to move the respiratory medium over the respiratory surface, where extraction can occur

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9
Q

Why is there more oxygen in air than in water?

A

There is Much more oxygen in air than in water in equilibrium with air, because of the low solubility coefficient α.

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10
Q

What is solubility coefficient?

A

The volume of gas which dissolves in one unit volume of the liquid at the temperature concerned.

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11
Q

1 L of air contains 210 mL oxygen, while
1 L water contains 7.7 mL oxygen (at 12°C)

what does this mean?

A

at the same amount of L air contains more oxygen

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12
Q

So, the concentration of oxygen in air is x what that in water at the same partial pressure / tension?

A

So, the concentration of oxygen in air is 30 × that in water at the same partial pressure / tension.

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13
Q

The concentration of oxygen in air is 30 × that in water at the same partial pressure / tension which means that the respiratory surface can be

A

smaller for same oxygen uptake.

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14
Q

To obtain 1L of Oxygen from the different media would have to process what?

A

4.8L of air; 98L of freshwater: 125L of seawater.

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15
Q

Which requires less work? Moving air or moving water?

A

Much less work has to be done moving air than moving water, to obtain the same oxygen.
This has implications for the design of the respiratory structures. In air, one way flow is less important.

An aquatic organism has to do more work and pass a greater volume of water over its Respiratory surface to obtain the same amount of oxygen as an air breather.

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16
Q

much less work has to be done moving air than moving water to obtain the same oxygen which has implications for

A

the design of the respiratory structures. In air, one way flow is less important.

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17
Q

for the respiratory structures in air one way flow is

A

less important

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18
Q

what does an aquatic organism have to do to obtain the same amount of oxygen as an air breather

A

an aquatic organism has to do more work and pass a greater volume of water over its respiratory surface to obtain the same amount of oxygen as an air breather

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19
Q

To obtain a given mass of Oxygen from water, you would have to move

A

100000x its mass in water.

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20
Q

When does the oxygen content of both air and water media decrease?

A

The oxygen content of both media decreases with increasing temperature

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21
Q

What happens to oxygen and water at constant oxygen tension?
At constant oxygen tension:

A

Oxygen concentration falls about 8% as temperature changes from
0-24°C

However, in water it falls as much as 40% for a similar change in temperature.

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22
Q

How much denser and viscous is water than air?

A

Water is about 800x denser than air. And about 63x more viscous

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23
Q

Why do aquatic organisms require more work to obtain a given volume of oxygen compared to air breathing organisms?

A

the amount of dissolved oxygen is fairly lower in water than air and also aquatic organisms like fishes obtain oxygen from water present in the dissolved state.
Since the quantity of dissolved oxygen in water is very much less as compared to the quantity of oxygen present in the air aquatic animals can breathe only dissolved oxygen, so to fulfill the need of required amounts of oxygen to the body cells for proper functioning the aquatic animals have to breathe faster as compared to terrestrial animals

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24
Q

What % of metabolic activity is involved in ventilation in humans and fish?

A

In resting humans, 1-2% of the metabolic activity is involved in ventilation of the lungs.

In resting fish, about 10-20% is directed at ventilation of the gills.

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25
Q

Advantages of living on water:

A
  1. the density of water is close to that of plasma, therefore respiratory
    structure such as gills are supported near neutral buoyancy.
    This keeps the entire filament suspended and in contact with the water.
  2. Air Breathing can cause evaporative loss of water. Therefore
    breathing structure must be kept moist.
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26
Q

why do gills stay suspended and in contact with water

A

the density of water is close to that of plasma, therefore gills are supported near neutral buoyancy which keeps the entire filament suspended and in contact with the water.

27
Q

what are the fundamental concepts of respiration?

A

-Oxygen must come in contact with the respiratory surface

-Oxygen must cross the gas exchange membrane by diffusion.

-Oxygen would only enter the organism if the partial pressure of oxygen
on the outside of the membrane is higher than on the inside.

28
Q

Oxygen must cross the gas exchange membrane by

A

diffusion

29
Q

Oxygen would only enter the organism if

A

the partial pressure of oxygen on the outside of the membrane is higher than on the inside.

30
Q

What are the different types of respiratory surfaces?

A
  1. Lungs
  2. External gills
  3. Internal gills
31
Q

what are lungs as a respiratory surface?

A

Lungs are Invaginations that contain the respiratory medium.
Lungs are invaginated into the body and contain the environmental medium

32
Q

what are external gills as a respiratory surface?

A

External gills – evaginations from the body which project directly
into the environment.

33
Q

what are internal gills as a respiratory surface?

A

evaginations of the body and enclosed in a superficial cavity.
It projects into the environmental medium where it is pumped through a superficial body cavity

34
Q

What is Ventilation?

A

forced movement of respiratory media to and from the respiratory surface.

35
Q

Ventilation can be either what?

A

can either be active or passive and it can also either be unidirectional or tidal

36
Q

What is the Difference between active and passive ventilation ?

A

In active - organism creates a ventilation current
In passive – environmental currents induced flow.

37
Q

What is the difference between unidirectional and tidal ventilation?

A

In Unidirectional
– the medium is pumped over the respiratory surface in only one direction
- New medium continuously flows over surfaces

In Tidal
– medium is inhaled and exhaled via the same path.
- Incoming medium mixed with “used” medium

38
Q

What are the types of flow at exchange surfaces?

A
  1. Concurrent flow
  2. Countercurrent flow
  3. Crosscurrent flow
39
Q

What are the Patterns of Flow at Exchange Surfaces?

A
  • Concurrent Flow
    – Body fluid and respiratory medium flow in same direction
    – Gradient reduced with distance
  • Countercurrent Flow
    – Body fluid and respiratory medium flow in opposite
    directions
    – Gradients sustained over distance
  • Crosscurrent Flow
    – Body fluid and respiratory medium flow at nonparallel angles
    to each other
    – Gradient slowly decreases with distance
40
Q

what happens in active ventillation

A

the organism creates a ventilation current

41
Q

what happens in passive ventilation

A

environmental currents induced flow

42
Q

what happens in unidirectional ventilation

A

-the medium is pumped over the respiratory surface in only one direction

-new medium continususly flows over surface

43
Q

what happens in tidal ventilation

A

-medium is inhaled and exhaled via the same path

-incoming medium mixed with “used” medium

44
Q

what happens in concurrent flow?

A

– Body fluid and respiratory medium flow in same direction

– Gradient reduced with distance

45
Q

what happens in Counter current flow?

A

– Body fluid and respiratory medium flow in opposite
directions

– Gradients sustained over distance

46
Q

what happens in Crosscurrent flow?

A

– Body fluid and respiratory medium flow at nonparallel angles
to each other

– Gradient slowly decreases with distance

47
Q

What is the difference between ventilation and respiration?

A

Ventilation is mechanical and involves the movement of air while respiration is physiologic and involves the exchanges of gases in the alveoli and the cells.

48
Q

What is the formula for the rate of O2 uptake?

A

Rate of O2 uptake (mLO2/min) =
Vmedium (CI – CE)

Rate of flow of the respiratory medium through the breathing organs = conc. Of oxygen in the inhaled air – conc. Of oxygen in exhaled air (the amount of O2 removed per unit volume of the respiratory medium.

49
Q

What Vmedium does stand for?

A

Rate of flow of the respiratory medium through the breathing organs

50
Q

What CI does stand for?

A

Conc. Of O2 in the inhaled medium

51
Q

What CE does stand for?

A

conc. Of O2 in the exhaled medium.

52
Q

What does CI – CE equal?

A

the amount of O2 removed per unit volume of the respiratory medium

53
Q

How do you calculate the % of O2 removal?

A

(CI – CE)/ CI * 100

54
Q

What does β stand for?

A

β = O2 utilization coefficient
an expression of how well an animal is able to use the O2 available in the medium

55
Q

Diagram of General Model of a Respiratory structure

A
56
Q

What does respiratory gas exchange efficiency depend on?

A
  1. Ventilation
  2. Diffusion
  3. Perfusion
  4. Relative direction of flow of blood and air or H2O (eg- concurrent vs countercurrent)
57
Q

how is gas exchange between medium and blood determined?

A

By 3 main processes:

  1. Ventilation = rate at which O2 is brought to respiratory surface
  2. Diffusion = rate of transfer of O2 from medium to blood across the
    respiratory surface
  3. Perfusion = rate of removal of blood from the respiratory surface

Each of these processes can be compared using the parameter:
Gas Conductance:

58
Q

what are the 3 process that determine how gas is exchanged between medium and blood

A
  1. ventilation
  2. diffusion
  3. perfusion
59
Q

how does ventilation determine how gas is exchanged between medium and blood

A

it determines the rate at which O2 is brought to the respiratory surface

60
Q

how does diffusion determine how gas is exchanged between medium and blood

A

it determines the rate of transfer of O2 from medium to blood across the
respiratory surface

61
Q

how does perfusion determine how gas is exchanged between medium and blood

A

it determines the rate of removal of blood from the respiratory surface

62
Q

each of the processes that determines how gas is exchanged between medium and blood can be compared using

A

the parameter gas conductance

63
Q

what does G mean?

A

Volume of gas transferred in ml per min per mm Hg partial pressure difference

64
Q

page 17

A