2. Renal Replacement Therapy

Question 1

Renal functions include (4)

Answer 1

Excretory functions
Water and electrolyte balance
Acid base balance
Renal endocrine function

Question 2

Renal dialysis is (3)

Answer 2

Passive process
Involves diffusion across concentration gradients
Allows intermittent correction of changes in plasma concentration of small molecules

Question 3

Types of renal dialysis (2)

Answer 3

Haemodialysis

Peritoneal dialysis

Question 4

Difference between haemodialysis and peritoneal dialysis (4)

Answer 4

Haemodialysis - can be actively altered, usually. 8hr session
Peritoneal dialysis - can happen continuously at home, can be done daily

Question 5

Renal endocrine replacement involves (3)

Answer 5

EPO replacement (injections)
Bone mass maintenance (vit D supplement, osteoporosis prevention)
HTN control (inactive RAAS - ACE inhibitors)

Question 6

Function of erythropoietin (EPO)

Answer 6

Maintains red cell mass

Question 7

Optimal treatment for ESRD

Answer 7

Renal transplantation (HLA matched donors)

Question 8

Renal transplantation function (3)

Answer 8

Restores renal function
Involves no dietary restrictions
Restores normal energy and fertility

Question 9

Transplant problems include (4)

Answer 9

Rejection
Immunosuppression
High cardiovascular mortality
Osteoporosis risk