2. Renal embryology (Kidney, Bladder, Suprarenal Gland) Flashcards

1
Q

What is the first structure to produce urine in an early fetus?

A

The mesonephros

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2
Q

From where is the collecting duct derived?

A

The collecting duct is derived from the ureteric bud.

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3
Q

Why does a fetus need to have a well-developed suprarenal gland?

A

Because of the requirement of DHEA to continue the pregnancy

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4
Q

What gives rise to the ureteric bud?

A

The caudal end of the mesonephric duct

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5
Q

What gives rise to the trigone?

A

The mesonephric duct growing downwards

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6
Q

What gives rise to the ureter, renal pelvis, and major and minor calyxes?

A

The ureteric bud

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7
Q

When do we see the appearance of the pronephros?

When do we see it degenerate?

A

Early week four

It degenerates by day 24 or 25

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8
Q

When do we expect to see the mesonephros producing urine?

A

From weeks 6 to 10

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9
Q

From where is the nephron derived?

A

The nephron is derived from the metanephrogenic blastema, which forms metanephric tubules, which become the nephron.

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10
Q

What gives rise to Bowman’s capsule?

A

The metanephric blastema

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11
Q

What is the pathway of structures leading to the formation of what will become the adult kidney?

(Hint: 5 structures)

A

Urogenital ridge
Nephrogenic cord
Pronephros
Mesonephros
Metanephros

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12
Q
A
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13
Q

What is derived from the pelvic part of the urogenital sinus?

A

The neck of the bladder, as well as:
in males, the prostatic urethra
in females, the entire urethra

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14
Q

What gives rise to the cortex of the suprarenal glands?

A

Epithelial cells from the intraembryonic coelom

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15
Q

What gives rise to the suprarenal medulla?

A

Neural crest cells

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16
Q

What forms the efferent ductules in men?

A

The mesonephric tubules, which produce some urine in early fetal life