2. Renal clearance

Question 1

define GFR

Answer 1

amount of filtrate that is produced from the blood flow per unit time(mL/min)

Question 2

define GFR

Answer 2

amount of filtrate that is produced from the blood flow per unit time(mL/min)

Question 3

define renal clearance

Answer 3

volume of plasma that is cleared of a substance in a unit of time

Question 4

calculation for clearance of a substance

Answer 4

(urine conc x urine flow rate)/ plasma conc

Question 5

what are 4 important characteristics of substances that can be used to measure GFR?

Answer 5

be produced at constant rate
not reabsorbed
not secreted
not synthesised or metabolised by kidney

Question 6

normal GFR

Question 7

what is excretion?

Answer 7

filtration + secretion - reabsorption

Question 8

calculation for filtration rate?

Answer 8

[P] x GFR

Question 9

calculation fro excretion rate?

Answer 9

[U] x V (urin flow rate)

Question 10

calculation for rate of secretion?

Answer 10

excretion rate - filtration rate

Question 11

define renal clearance

Answer 11

volume of plasma that is cleared of a substance in a unit of time

Question 12

calculation for clearance of a substance

Answer 12

(urine conc x urine flow rate)/ plasma conc

Question 13

what are 4 important characteristics of substances that can be used to measure GFR?

Answer 13

be produced at constant rate
not reabsorbed
not secreted
not synthesised or metabolised by kidney

Question 14

normal GFR

Question 15

what is excretion?

Answer 15

filtration + secretion - reabsorption

Question 16

calculation for filtration rate?

Answer 16

[P] x GFR

Question 17

calculation fro excretion rate?

Answer 17

[U] x V (urin flow rate)

Question 18

calculation for rate of secretion?

Answer 18

excretion rate - filtration rate