✅2 - Nucleic Acids Flashcards
What are individual nucleotides made up?
- a pentose sugar
- a phosphate group
- a nitrogen containing organic base (C,T,U,A,G)
How are the 3 components joined?
As a result of condensation reactions
What is a phosphodiester bond?
The bond between the deoxyribose of one mononucleotide and the phosphate group of another
A=
Adenine
T=
Thymine
G=
Guanine
C=
Cytosine
U=
Uracil
What is a dinucleotide?
When two nucleotides are by need together
What is a polynucleotide?
The continued linking of mononucleotides forming a long chain
What 4 bases does RNA have?
A,C,G,U
Describe the structure of RNA:
A single, relatively short polynucleotide chain where the pentose sugar is always ribose.
What are the 3 types on RNA involved in?
- transfers genetic information from DNA to the ribosomes
- ribosomes are made up of a type of RNA
- involved in protein synthesis
Describe the structure of DNA:
The pentose sugar deoxyribose, making up two strands of polynucleotides, each of which are extremely long and joined by hydrogen bonds
What are the complimentary pairs?
A-T
G-C
Which are the Purine bases?
Adenine and Guanine
Which are the Pyrimidine bases?
Cytosine and Thymine
How many bases in mRNA code for an amino acid?
Three, known as a codon
What does the order of the codons specify?
The type, number and sequence of the amino acids
How is the DNA molecule adapted to carry out its functions?
- it is a very stable structure which rarely mutates
- two separate strands joined only by hydrogen bonds can separate easily during replication
- extremely large molecule which can therefore carry a lot of genetic information
- base pairing leads to the DNA being able to replicate and to transfer information as mRNA
Why is DNA a stable molecule?
- the phosphodiester backbone protects the more chemically reactive organic bases inside the double helix
- hydrogen bonds link the organic base pairs forming bridges between phosphodiester backbones. As there are three hydrogen bonds between G and C, the higher the proportion of the bonds, the more stable the DNA