2 Nephron Physiology

Question 1

Secondary Active Transport

Answer 1

Molecules (Glucose, Amino Acids, Ions, Metabolites) attach to Na to move through the cell wall.
Uses energy indirectly by being coupled to another solute

Question 2

Secondary Active Secretion into Tubules

Answer 2

Mechanism of HCO3 reabsorption and Na/H exchange in proximal tubule and thick loop of Henle.
Uses energy indirectly by being coupled to another solute

Question 3

Where is the only region in the nephron where carbonic anhydrase is present on the luminal membrane?

Answer 3

Proximal Tubule

Question 4

Where is the target for lasix?

Answer 4

Thick ascending segment of Henle’s Loop.

Question 5

Where is the only nephron segment that Cl is actively transported and location of the NA-K-Cl pump?

Answer 5

Thick ascending segment of Henle’s Loop

Question 6

What provides feedback control of GFR and blood flow with in the nephron?

Answer 6

Juxtaglomerular complex (first portion of the distal tubule)

Question 7

What do Principal Cells do?

Answer 7

Reabsorb Na and H2O from the lumen and secrete K into the lumen.

Question 8

What do Intercalated cells do?

Answer 8

Reabsorb bicarbonate and K ions from the lumen and secrete H into the lumen.
(Important for acid-base balance)