2. Immunity & Vaccines Flashcards
herd immunity
reduce occurrence of disease.
those not vaccinated less likely to catch disease.
vaccines contain
antigens
free or attached to dead/attenuated pathogen
disadvantage of taking vaccine orally
broken down by enzymes
could be too large to be absorbed into blood
what do vaccines do
contain antigens
cause body to produce memory cells without pathogen causing disease
immune - no symptoms
antigentic variation is caused by
changes in genes of pathogens
why does antigenic variation cause you to get ill again
memory cells from 1st infection don’t recognise different antigens
has to carry out primary response
e.g. of pathogens that show antigenic variation
influenza
HIV virus
different antigens =
new strain of virus
active immunity
immune system makes its own antibodies after being stimulated by an antigen
natural - immune after catching a disease
artificial - immune after vaccination
passive immunity
given antibodies made by a different organism. own immune system doesn’t produce any.
natural - baby receives antibodies through placenta/breast milk
artificial - injected with antibodies from someone else
active vs passive immunity
A requires exposure to antigen. P doesn’t
A takes while for protection to develop. P immediate protection
A memory cells produces. P not produced
A long term protection memory cells. P short term. antibodies broken down.