2. Homeostasis Pt 5 Flashcards
What does Urine contain?
- mostly water, with varying amounts of slats & urea dissolved in it
- these are all colourless
- but the yellow part of the urine is due to urobilins which are created by the liver as it breaks down haemoglobin
Quickly go through the the states urea goes through to be turned into urine?
- Urea is made the liver
- Flows in the blood
- Urea, ions, glucose and water pass into kindness tubules
(Glucose, some ions and some water is reabsorbed) - Urea, some ions and some water flows down ureters
- Urine is stored in the bladder
- Urine is expelled out of urethra
What substances are present in blood?
- Cells
- protein
- Glucose
- Water
- Mineral ions
- Urea
What substances are present in kindness tubules?
- Glucose
- Water
- Mineral ions
- Water
What substances are present in urine?
- Some water
- Some mineral ions
- Urea
Where is ADH produced?
It’s produced by the pituitary gland
What does ADH stand for and what does it do?
- anti-diuretic hormone
- it increases the permeability of the kidney tubules
- it will increase the amount of water re-absorbed back into the body
Explain what happens in your body when you become dehydrated
- Hypothalamus detects high concentration of solutes in blood.
(Hypothalamus creates the feeling of thirst) - Pituitary gland releases ADH
- kidneys maintain blood water level high.
(By retaining water and making Urine more concentrated with salts and urea)(when the person drinks water) - So less water is lost in urine (urine is more concentrated)
- Blood water level returns to normal
What happens your water levels are too high?
- Hypothalamus detects low solute concentration
- Pituitary releases less ADH
- Kindness reabsorbs less water
What 4 things cause kindness failure?
-Genetic diseases
-infections
-drugs/poisons
-physical damage
This can lead to dangerous toxins to build up and your salt and water balance will be disrupted
What are the 2 solutions to kidney failure?
- transplant
- kidney dialysis (this is a temporary solution)
How does a kidney dialysis work?
- blood is sent to a partially permeable artificial membrane
- this prevents blood cells and large proteins from leaving the blood but allows small, soluble molecules to move freely
- the fluid around the membranes has no urea in it creating a steep concentration gradient and causing urea to diffuse out of the blood
- the dialysis fluid also has the correct concentration of glucose, ions and water which will diffuse either way until the blood reaches the right levels
What are disadvantages of the kidney dialysis?
- it takes approx 8 hours to complete and is usually done in hospital 2 or 3 times a week
- this can be very disruptive for your normal life
How does a kidney transplant work?
- its taken from an appropriate donor
- and attached to the blood vessels and ureter of the patient
What’s the risk of kidney transplants? How is this risk reduced?
- every person has different antigens on the surface if their cells
- the immune system of the recipient may attack the new kidney, causing it to be rejected and destroyed
- this is reduced by matching donors abs recipients are closely as possible by checking they’re blood type and if they have similar surface antigens