2. Growth and development Flashcards
What is the bilaminar disc?
- ectoderm and endoderm
What is the trilaminar disc?
- endoderm, ectoderm and mesoderm
What does the ectoderm form?
- skin, nails, teeth etc
What does the mesoderm form?
Muscles, bone
What does the endoderm form?
- gut
What symptoms are present in ectodermal dysplasia?
- problem with ectoderm
- sparse hair
- periorbital wrinkling
- dysplastic nails
- congenitally absent teeth
- peg shaped teeth
What forms on the 26th day?
- frontal prominence
- maxillary process
- mandibular process
What forms on the 27th day?
- odontogenic epithelium
What forms on the 34th day?
- lateral nasal process
- medial nasal process
- nasal pit
What happens on 36th and 38th day?
Fusion of processes, eg. maxillary and mandibular process. And medial and lateral nasal process.
What happens in the 7th, 8th and 9th week?
- in the 7th week, the tongue is meant to drop down to allow the shelves to fuse correctly
- the primary palate is formed from the frontonasal processes, forming the premaxilla and fusing with the maxillary processes posteriorly
- the secondary palate is formed by fusing of the right and left palatal shelves of the maxilla
- failure of these processes to fuse gives rise to cleft lip/alveolus/palate
How does the mandible form?
from fusion of the bilateral prominences
What cartilage is the mandible made from?
- meckel’s cartilage forms the basis of the mandible as well as the structures of the inner ear
- therefore aberrations of the mandible can therefore lead to hearing difficulties and should be considered when faced with poorly developed mandible
How does a child’s mandible differ from adults?
Child’s mandible is smaller with a far shorter ramus
PHARYNGEAL ARCHES SLIDE 14
What is Treacher Collins syndrome?
Problem with the first pharyngeal arch
- eyes with downward slant
- small flattened cheekbones
- small steeply angled jaw
- small oddly shaped ears
- may have cleft palate
Where can clefts affect?
- the lip, alveolus and palate. If it affects the alveolus, the child may not have the full complement of teeth as the bone has not fused
- clefts of the mandible and face are very rare
What is the definition of a cleft?
Failure of developing palatal shelves and/or frontonasal prominence to fuse together
What is the incidence of clefts?
CLP- 1 in 7000 live births
Palate- 1 in 200
Who and where are clefts most common in?
Males and left hand side
What are associated syndromes with clefts?
- Downs syndrome
- Treacher Collisns
- Pierre Robin
- Klippel-Fiel
How does the mandible join and as a result which tooth is most likely to be missing?
- the mandible joins along the symphisis with left and right sides coming together. If there is a disruption in the union, it may cause absence of lower anterior 1
How does the maxilla join and as a result which tooth is most likely to be missing?
- the premaxilla joins the posterior maxilla at a region where the lateral incisors are
- so lateral incisor most likely to be missing if there is disruption in the union
What are morphogenetic fields?
- the arch is divided into segments
- the most anterior tooth in each segment is the key tooth, most stable
- eg, molars=6, premolars=4, anterior=1
- stability is in terms of reliable size and occurence
- this theory supports common patterns of hypodontia
What is the cranium like at birth?
- 60-65% of adult volume
- has sutures open
- has 6 fontanelles
What are the teeth like at birth?
- primary teeth are partly calcified
- teeth present at or very shortly after birth are called natal teeth