2 - Anesthesia Flashcards
Normal pH of local anesthetics:
5.5 - 6.0
Doesn’t work well w/ infected tissue (more acidic)
Can add bicarb to buffer
How do most local anesthetics work?
Block Na channels and impair propagation of AP
Thinner myelinated nerve fibers are more easily BLK
Advantages of epi in locals
Vasoconstrictor
Increased duration of action
Decreased bleeding and volume needed to anesthesia
Disadvantages of epi in locals
Increased myocardial activity
Tachycardia
HTN
Dysrhythmias
Avoid pts w/ known CV dz, HTN, DM, thyroidtoxicosis
Describe the ideal anesthetic
Short latency Superior penetration Non-addictive Completely reversible Low toxicity Stable and water soluble Non-irritating Inexpensive
MC adverse effects of local anesthetic
Urticaria
Erythema
Edema
Dermatitis
Toxicity from locals - prodromal sxs
Cicrumoral numbness
Tinnitus
Lightheaded / dizzy
Tingling Metallic taste in mouth
Toxicity from locals - CV problems
HTN then HOTN
Tachy or brady
V-fib - CV collapse
Toxicity from locals - severe CNS:
Tonic-clonic activity
ALOC -> unconsciousness
What do you do prior to injecting to avoid intravascular injection?
Aspirate first
Bupivicaine not recommended for:
Kids under 12yrs
Method for injecting local
Large coverage with one puncture (longer, small gauge needle
Bent 45 degrees, hub the needle, inject as you withdraw
Sequence of clinical anesthesia
Vasodilation - loss of symp tone
Loss of
- Pain/temp sensation
- Pressure sensation
- Motor fx
Peripheral nerve blocks - common sites?
Digit blocks - (Common w/ rib blocks as well)
Plantar aspect of foot
Palmar aspect of hand
Max dose Bupivicaine?
2mg/kg up to 100mg
Where is epidural anesthesia injected?
Into the epidural space, NOT the CSF
Describe epidurals
Skin taped Cath - Req continuous inf of LRG anesthetic volume
Acute complications of nerve blocks
HOTN (neurogenic shock) - txt w/ IVF/pressors (v-con)
High spinal - brady-c, HOTN, arm tingling, and respiratory distress (txt-ventilate)(diaphragm C3-C5)
Cauda equina - bladder/bowel dysfx, m/s alts in legs
Dermatomes - Clavicles, nipples, umbilicus
Diaphragm innervation
Diaphragm inervation C3-C5
Clavicles - C5
Nipples - T4
Umbilicus - T10
Conscious sedation provides
Analgesia and anxiolysis
Minimally depressed LOC
Usual combo for conscious sedation?
Benzo + narcotic
OR
Propofol + narcotic
Intubation in conscious sedation?
Nope - patient maintains their own airway
Nice perks of conscious sedation?
Still follows commands (verbal stimuli)
Doesn’t remember any of it later (antegrade amnesia)
Examples of procedures in which conscious sedation is used
Bronchoscopy EGD/colonoscopy Thoracostomy Closed reduction of fx’s Procedures in kids
What does propofol provide (and not provide)?
It’s a sedative-hypnotic
So… anxiolysis, muscle relaxant, anticonvulsant
BUT
NO DIRECT ANALGESIC EFFECT
Patient safety during conscious sedation
Req crash cart
- Follow SOP’s
- NPO prior
- ASA class I and II patients
- Dedicated staff