2 Flashcards
functions of secretory IgA
Inhibits bacterial attachment
and metabolism
Neutralizes bacterial toxins & enzymes
A peroxidase enzyme found in saliva, tears, milk
lactoperoxidase
function of lactoperoxidase
H2O2 mediated oxidation/denature of microbial substances
function of lactoferrin
removes iron from solution –> bacteriocidal
Salivary components that promote stability of Enamel
Calcium Binding Proteins
- Statherin (Phosphoprotein)
- Proline rich proteins (PRPs)
Statherin binds calcium ion (Ca2+), prevents –
precipitation
Statherin inhibits – of supersaturated calcium phosphate in oral fluid
spontaneous precipitation or crystallization
function of PRPs
inhibit calcium phosphate crystal growth
where is lysozyme present?
saliva and gingival crevicular fluid
lysozyme has – properties
anti-bacterial
lysozyme is effective against – bacteria
gram +
lysozyme breaks down –
cell wall (protein lysis)
lysozyme inhibits –
adhesion to tooth surface and glucose uptake and acid production
what is caries?
chemically-controlled acid driven dissociation of the inorganic salt known as hydroxyapatite
what causes caries?
presence of biofilm-associated bacteria which produce organic acids with fermentation of sugars