2 Flashcards

1
Q

functions of secretory IgA

A

Inhibits bacterial attachment
and metabolism
Neutralizes bacterial toxins & enzymes

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2
Q

A peroxidase enzyme found in saliva, tears, milk

A

lactoperoxidase

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3
Q

function of lactoperoxidase

A

H2O2 mediated oxidation/denature of microbial substances

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4
Q

function of lactoferrin

A

removes iron from solution –> bacteriocidal

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5
Q

Salivary components that promote stability of Enamel

A

Calcium Binding Proteins

  • Statherin (Phosphoprotein)
  • Proline rich proteins (PRPs)
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6
Q

Statherin binds calcium ion (Ca2+), prevents –

A

precipitation

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7
Q

Statherin inhibits – of supersaturated calcium phosphate in oral fluid

A

spontaneous precipitation or crystallization

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8
Q

function of PRPs

A

inhibit calcium phosphate crystal growth

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9
Q

where is lysozyme present?

A

saliva and gingival crevicular fluid

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10
Q

lysozyme has – properties

A

anti-bacterial

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11
Q

lysozyme is effective against – bacteria

A

gram +

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12
Q

lysozyme breaks down –

A

cell wall (protein lysis)

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13
Q

lysozyme inhibits –

A

adhesion to tooth surface and glucose uptake and acid production

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14
Q

what is caries?

A

chemically-controlled acid driven dissociation of the inorganic salt known as hydroxyapatite

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15
Q

what causes caries?

A

presence of biofilm-associated bacteria which produce organic acids with fermentation of sugars

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16
Q

Sucrose is required for the production of – which promote bacterial plaque formation and stability

A

water insoluble bacterial glucans

17
Q

What is special characteristic of the infectious agent that causes caries?

A

it’s transmissible

18
Q

Is caries genetically inherited?

A

no

19
Q

how can you reduce caries risk?

A

Reduce carbohydrate intake
Reduce the bacterial bioburden
Eliminate specific bacterial species*
Enhance salivary defense molecules