2 Flashcards

1
Q

High level of free PSA are most likely the result of?

A

Benign prostatic hypertrophy

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2
Q

PSA conc found in normal adult males below the age of 45 would most likely be _____ ng/ml

A

0-4

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3
Q

A 75 year old male pt presents with complaint of severe low back pain, multiple urinary problems, significant unexplained weight loss, pallor and malaise. His PSA is 25 ng/ml. Prostate is enlarged. What is the most likely diagnosis based on these criteria?

A

Prostate cancer

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4
Q

DRE palpatory findings in a patient are as follows: asymmetrical, stony hard irregular nodule, 1cm protrusion into the rectum, media sulcus is obliterated. These findings would be most indicative of:

A

Prostate cancer

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5
Q

The serum PSA level divided by the prostate volume is:

A

A definition of PSA Density and A better differentiator of prostate problems when combined with serum PSA (A & C)

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6
Q

Which of the following is TRUE about cryptorchid patients in general?

A

Testis is arrested in normal path of descent

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7
Q

For testosterone to act on the prostate (to cause enlargement), it must first be converted to:

A

Dihydrotestosterone (DHT)

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8
Q

Prostate cancer dev from cancer in situ to clinical presentation is about _____ years

A

10-12

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9
Q

A 14 yo male patient present with a suddenly developed severe pain in one testicle, followed by swelling of the entire testicle and scrotal reddening. Pt also has lower abdominal pain and nausea and vomiting. The pt has a history of unilateral cryptorchidism and recent trauma to the groin. There is no fever. What is most likely clinical consideration for this pt?

A

Testicular torsion

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10
Q

Which of the following is a risk factor for testicular cancer?

A

Cryptorchidism

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11
Q

Accounts for 1% of all male cancers; the most common cancer in males aged 15-34%; often asymptomatic in early stages best describes:

A

Testicular cancer

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12
Q

Lab test most pertinent to a suspected case of prostate cancer would include

A

Acid and Alkaline phosphatase

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13
Q

The most common presenting complaint in a 28 year old male is a painless unilateral swelling or nodule in the testis, usually as an incidental finding by the pt or his sexual partner. Scrotal or lower abdominal pain (dull ache, heaviness) occurs in about one third of these pos. Pt also has an abdominal mass and extensive lymphadenopathy. No history of trauma. Pt has a history of unilateral cryptorchidism. This is a profile typical of _____.

A

Testicular cancer

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14
Q

The thin layer of connective tissue that separates the prostate from the rectum is known as

A

Denonvillier’s fascia

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15
Q

A 51 yo male presents with a history of nocturne, frequency, and urgency about half the time. He states that fro the last month he has had difficulty starting and maintaining his urine stream ( has to push or strain) more than half the time. He always feels like his bladder is not empty after urinating. On PE, the prostate is found to be enlarged, contender, rubbery, and boggy. His PSA lvl is 2.7 ng/ml. Does not have a fever. Which of the following is the most likely diagnose based on the data collected so far?

A

BPH

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16
Q

Prostate cancer can be compared to ____ cancer, as they both are unusually similar in respect to: lifetime risks, age at diagnosis, response to hormone therapy, new cases annually

A

Breast

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17
Q

DRE placatory findings in a pt are as follows: symmetrical, boggy, smooth, rubbery and median sulcus is partially obliterated. This is?

A

BPH

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18
Q

PSA levels can be elevated by which of the following?

A

AOTA

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19
Q

If the prostate gland becomes malignant and cancer cells begin to spread, the metastatic will most likely go to the?

A

lumbar spine

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20
Q

70% of prostate cancer tissue is found in the ____ zone

A

Peripheral

21
Q

Brachytherapy is a radiotherapy treatment most commonly used for ____ cancer

A

Prostate

22
Q

A weak urine steam with decreased caliber is a classic symptom for?

A

BPH

23
Q

BPH often begins in the transition zone which surrounds the

A

Urethra

24
Q

According to autopsy studies, in men over age 90 there is a ____%

A

100

25
Q

A gleason grade 5 (this is not the Gleason score where the 2 grades are added together) would be indicative of:

A

2 of the above

26
Q

Significant findings w/ the PSA Velocity Test would be an increase of ___ ng/ml/yr.

A

.75

27
Q

T or F: In order to protect the fertility of the cryptorchid patient, their testes should be in the crotum by age 1.

A

True

28
Q

Dorsal curvature of the penis is known as:

A

Peyronie’s disease

29
Q

T/F: Men can perform their own DRE prostate exam.

A

True

30
Q

Prostate cancer kills about __ men per year in U.S.

A

32,000

31
Q

T/F: 80% of testicular cancer patients will have systemic metastatic signs at the time of diagnosis.

A

False

32
Q

A 25 Y.O. male patient recently experienced groin trauma presents w/ painless scrotal swelling that arises in the morning and becomes larger and tense throughout the day. Transillumination of scrotal fluid. These describe what?

A

Hydrocele

33
Q

A testicular cystic mass containing thin white cloudy fluid and is freely movable describes:

A

Spermatocele

34
Q

Downward/ventral curvature of the penis

A

Chordee

35
Q

A 21 Y.O. man recently recovered from the mumps and complains of a swollen and sudden onset of a painful left testicle. Physical exam shows testicular tenderness, enlargement , and hardening. Most likely?

A

Orchitis

36
Q

Possible tumor marker(s) for testicular cancer would be?

A

All of the above

lactate dehydrog., alpha feto-protein, human chorionic gonadotropin

37
Q

The group w/ highest incidence of cryptorchidism would be:

A

Premature infant boys

38
Q

One characteristic of testicular cancer:

A

Testicular dysgenesis is a risk factor

39
Q

Patient w/ priapism would be complaining of:

A

Unrelenting erection

40
Q

A 25 Y.O. male presents w/ a history of recurrent UTI, fever, malaise, and dysuria. Most likely:

A

Prostatitis

41
Q

Estrogens and progestins given to mothers during pregnancy are known to increase incidence of:

A

Hypospadia

42
Q

The foreskin becomes trapped behind the glans penis and cannot be pulled back to its normal position covering the glans. This is known as:

A

Paraphimosis

43
Q

A 30 Y.O. sexually overactive male patient presents w/ fever, rapid progressive onset of scrotal pain and urethral discharge. Only the superior portion of the testes is tender, enlarged and indurated. Most likely condition?

A

Epididymitis

44
Q

Define hypospadia

A

Opening of penis is on the underside of the hand

45
Q

Define androgen dependent prostate cancer (ADPC)

A

Early stage tumor growth that requires androgens for proliferation and regulation.

46
Q

List 5 conditions/events that can elevate PSA levels

A

Prostatitis, Benign prostatic hyperplasia, UTI, Normal aging, Post ejaculation

47
Q

List 5 natural treatments that prostate patients might benefit from

A

Pumpkin/watermelon seed, Corn silk, Consuming more fish (Omega 3’s), Stinging nettle, Palmetto extract, Adequate water

48
Q

Write 3 ways in which the signs and symptoms of BPH and prostate cancer may differ

A

Increase of PSA in BPH not as steep, dribbling of urine seen in BPH, Cancer has elevated Alkaline phosphatase