2 Flashcards
What is the formulation of Intralipid used in lipid rescue therapy?
20% intralipid
What is the primary use of Intralipid?
As an antidote of last resort in cardiotoxic overdoses of lipophilic agents
In addition to its use as an antidote, what is another purpose of Intralipid?
Source of lipid and calories in parenteral nutrition
What is the initial bolus dose of Intralipid for cardiotoxic overdoses?
1.5 mL/kg
How much Intralipid would a 70kg adult receive as an initial bolus?
About 100 mL
What is the continuous infusion rate of Intralipid following the initial bolus?
0.25 mL/kg/min for 30-60 minutes
How much Intralipid would a 70kg adult receive over 30 minutes during continuous infusion?
About 600 mL
How many times can the initial bolus of Intralipid be repeated for persistent asystole?
1-2 times
At what intervals can the bolus of Intralipid be repeated?
5 minute intervals
What should be done if blood pressure declines during Intralipid infusion?
Double the infusion rate
True or False: Intralipid can be used as an antidote for all types of overdoses.
False
